Peptide

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Ac-DEVD-AFC
Ac-DEVD-AFC

Artikelnummer: ABD-13401

A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Anwendung: Caspase-3 substrate
CAS 201608-14-2
139,00 €
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(Z-DEVD)2-R110
(Z-DEVD)2-R110

Artikelnummer: ABD-13430

Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Anwendung: Caspase-3 substrate, Caspase-7 substrate
139,00 €
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Ac-DEVD-AMC
Ac-DEVD-AMC

Artikelnummer: ABD-13402

A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Anwendung: Caspase-3 substrate
CAS 169332-61-0
139,00 €
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(Ac-PAL)2R110
(Ac-PAL)2R110

Artikelnummer: ABD-13467

The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Anwendung: Protease substrate
139,00 €
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3,3',5'-Triiodo-L-thyronine
3,3',5'-Triiodo-L-thyronine

Artikelnummer: Cay17598-50

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Schlagworte: 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine
Anwendung: TR Delta alpha1 activator
CAS 5817-39-0
MW: 651 D
ab 114,00 €
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Angiotensin II (human) (acetate)
Angiotensin II (human) (acetate)

Artikelnummer: Cay17150-25

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Schlagworte: 5-L-isoleucine-angiotensin II, acetate
Anwendung: Peptide hormone
CAS 68521-88-0
MW: 1046.2 D
ab 34,00 €
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Glucagon (hydrochloride)
Glucagon (hydrochloride)

Artikelnummer: Cay24204-1

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
Schlagworte: glucagon (swine)
Ursprungsart: swine
CAS 19179-82-9
MW: 3482.8 D
ab 117,00 €
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PI-3 Kinase Lipid Substrate
PI-3 Kinase Lipid Substrate

Artikelnummer: BPS-40560

PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
Anwendung: PI-3 kinase substrate
569,00 €
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NEU
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (trifluoroacetate salt)
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (trifluoroacetate salt)

Artikelnummer: Cay35865-1

N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (fNLFNYK) is a synthetic chemotactic peptide. It binds to the formyl peptide receptor (FPR, Kd = 2.2 nM). fNLFNYK has been conjugated to various fluorophores to monitor FPR internalization.Formal Name: N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine,...
Schlagworte: fNLFNYK, N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine, monotrifluoroacetate salt
Anwendung: Formyl peptide receptor (FPR1) binding, chemotactic peptide
CAS 2918767-97-0
MW: 938.1 D
ab 39,00 €
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NEU
Atogepant
Atogepant

Artikelnummer: Cay35899-1

Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
Schlagworte: (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-...
Anwendung: CGRP receptor (CALCRL) antagonist
CAS 1374248-81-3
MW: 603.5 D
409,00 €
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NEU
KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt)
KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt)

Artikelnummer: Cay38850-10

KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein beta-casein. It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria. KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not...
Schlagworte: L-lysyl-L-alpha-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-alpha-glutamyl-...
Anwendung: Beta-casein peptide fragment
MW: 1461.7 D
ab 34,00 €
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NEU
Bradykinin (2-9) (trifluoroacetate salt)
Bradykinin (2-9) (trifluoroacetate salt)

Artikelnummer: Cay39723-1

Bradykinin (2-9) is a metabolite of the endogenous vasodilator peptide bradykinin (Cay-37408). It is formed from bradykinin via N-terminal cleavage by carboxypeptidase.Synonyms: BK (2-9), (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Molecular Formula: C44H61N11O10 . XCF3COOH. Formula...
Schlagworte: (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, BK (2-9), H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, (Des-Arg1)-BDK
Anwendung: Bradykinin metabolite
MW: 904 D
ab 61,00 €
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