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Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Anwendung: | Caspase-3 substrate |
CAS | 201608-14-2 |
139,00 €
Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
139,00 €
Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Anwendung: | Caspase-3 substrate |
CAS | 169332-61-0 |
139,00 €
Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Anwendung: | Protease substrate |
139,00 €
Artikelnummer: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Schlagworte: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
Anwendung: | TR Delta alpha1 activator |
CAS | 5817-39-0 |
MW: | 651 D |
ab 114,00 €
Artikelnummer: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Schlagworte: | 5-L-isoleucine-angiotensin II, acetate |
Anwendung: | Peptide hormone |
CAS | 68521-88-0 |
MW: | 1046.2 D |
ab 34,00 €
Artikelnummer: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
Schlagworte: | glucagon (swine) |
Ursprungsart: | swine |
CAS | 19179-82-9 |
MW: | 3482.8 D |
ab 117,00 €
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
Anwendung: | PI-3 kinase substrate |
569,00 €
NEU
Artikelnummer: Cay35865-1
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (fNLFNYK) is a synthetic chemotactic peptide. It binds to the formyl peptide receptor (FPR, Kd = 2.2 nM). fNLFNYK has been conjugated to various fluorophores to monitor FPR internalization.Formal Name: N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine,...
Schlagworte: | fNLFNYK, N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine, monotrifluoroacetate salt |
Anwendung: | Formyl peptide receptor (FPR1) binding, chemotactic peptide |
CAS | 2918767-97-0 |
MW: | 938.1 D |
ab 39,00 €
NEU
Artikelnummer: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
Schlagworte: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
Anwendung: | CGRP receptor (CALCRL) antagonist |
CAS | 1374248-81-3 |
MW: | 603.5 D |
409,00 €
NEU
Artikelnummer: Cay38850-10
KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein beta-casein. It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria. KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not...
Schlagworte: | L-lysyl-L-alpha-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-alpha-glutamyl-... |
Anwendung: | Beta-casein peptide fragment |
MW: | 1461.7 D |
ab 34,00 €
NEU
Artikelnummer: Cay39723-1
Bradykinin (2-9) is a metabolite of the endogenous vasodilator peptide bradykinin (Cay-37408). It is formed from bradykinin via N-terminal cleavage by carboxypeptidase.Synonyms: BK (2-9), (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Molecular Formula: C44H61N11O10 . XCF3COOH. Formula...
Schlagworte: | (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, BK (2-9), H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, (Des-Arg1)-BDK |
Anwendung: | Bradykinin metabolite |
MW: | 904 D |
ab 61,00 €