Anti-TLR8 (Toll-like Receptor 8, CD288, UNQ249/PRO286) / USBio Product-Datasheet T8050-85J
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Anti-TLR8 (Toll-like Receptor 8, CD288, UNQ249/PRO286)

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IC IF
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.
Catalog #T8050-85J
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 2ug/ml
Western Blot: 0.5-2ug/ml
Immunocytochemistry: 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlDaudi cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human TLR8 (IN).
SpecificityRecognizes human TLR8. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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