Anti-TLR8 (Toll Like Receptor-8), clone 6D83 / USBio Product-Datasheet T8050-84B |
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Biomol GmbH Waidmannstr. 35 22769 HAMBURG info@biomol.de www.biomol.de |
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Anti-TLR8 (Toll Like Receptor-8), clone 6D83 |
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| The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kD. | |
| Catalog # | T8050-84B |
| Applications | |
| Suitable for use in Flow Cytometry and Western Blot Other applications not tested. | |
| Recommended Dilution | Flow Cytometry: 2-5ug/10e6 cells. |
| Western Blot: 1-3ug/ml. | |
| Optimal dilutions to be determined by the researcher. | |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| CAS Number | n/a |
| Clone Type | Monoclonal |
| Isotype | IgG1 |
| Clone No | 6D83 |
| Host | Mouse |
| Source | Human |
| Concentration | ~0.5mg/ml |
| Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.02% sodium azide. |
| Purity | Purified by Protein G affinity chromatography. |
| Immunogen | Synthetic peptide corresponding to aa 750-850 of the cytoplasmic portion of human TLR8 (Toll-like receptor 8). |
| Specificity | Recognizes human TLR8 at ~120kD. Species Crossreactivity: mouse. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
Questions or comments about this product? Inquire here. |
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| Download Specifications for Anti -TLR8 (Toll Like Receptor 8, Toll-like Receptor 8, TLR 8, CD288, CD288 Antigen, MGC119599, MGC119600) |
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