Anti-CCR9, CT (Chemokine-binding Protein 2, Chemokine-binding Protein D6, C-C Chemokine Receptor D6, CCR-9, Chemokine Receptor CCR-9, CC-Chemokine Receptor CCR-10, CCBP2, CCR10, CMKBR9) / USBio Product-Datasheet C2099-73R |
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Anti-CCR9, CT (Chemokine-binding Protein 2, Chemokine-binding Protein D6, C-C Chemokine Receptor D6, CCR-9, Chemokine Receptor CCR-9, CC-Chemokine Receptor CCR-10, CCBP2, CCR10, CMKBR9) |
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| CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. | |
| Catalog # | C2099-73R |
| Applications | Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. |
| Recommended Dilution | ELISA: 1:1,000 |
| Western Blot: 1:100-1:500 | |
| Immunohistochemistry: 1:50-1:100 | |
| Optimal dilutions to be determined by the researcher. | |
| Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Source | Human |
| Concentration | ~0.25mg/ml |
| Form | Supplied as a liquid in PBS, 0.09% sodium azide. |
| Purity | Purified by Protein G affinity chromatography. |
| Immunogen | Synthetic peptide selected from the C-terminal region of human CCBP2 (KLH). |
| Specificity | Recognizes human CCBP2. Species Crossreactivity: mouse. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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