Anti-TLR8 (Toll Like Receptor-8), Phycoerythrin conjugated, clone 6D83Art Nr.: T8050-84D, USBio
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|The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kD.|
|Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. |
|Recommended Dilutions|| |
|Flow Cytometry (Intracellular): 0.5-2ug/10e6 cells |
|Optimal dilution determined by the researcher. |
|Storage and Stability||May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.|
|Form||Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Labeled with R-Phycoerythrin (PE) |
|Purity||Purified by Protein G affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to aa750-850 of the cytoplasmic portion of human TLR8.|
|Specificity||Recognizes human TLR8 at ~120kD. |
|Important Note||This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.|
This product is offered by Biomol for research purposes only.
Not for diagnostic purposes or human use.
It may not be resold or used to manufacture commercial products without written approval of Biomol GmbH.