Anti-PODXL, clone 5D4

Art Nr.: Pro-30205, ProMab
Biomol GmbH
Waidmannstr. 35
22769 HAMBURG
info@biomol.de
www.biomol.de
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Specification
Entrez GeneID 5420
Aliases PC; PCLP; Gp200; PCLP-1; MGC138240
Clone# 5D4
MW 49kDa
Host/Isotype Mouse IgG1
Storage 4?; -20? for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human PODXL expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Application
WB 1/500 - 1/2000
IHC N/A
ICC N/A
FCM N/A
ELISA 1/10000
Description
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte)
References
1. Blood. 2009 Jan 22;113(4):816-26.
2. Am J Physiol Cell Physiol. 2009 Mar;296(3):C505-13.
Related Products

Elisa

Red: Control Antigen (100ng);
Purple: Antigen (10ng);
Green: Antigen (50ng);
Blue: Antigen (100ng);

Western Blot

Figure 1: Western blot analysis using PODXL mAb against human PODXL (AA: 109-324) recombinant protein. (Expected MW is 47.3 kDa)


This product is offered by Biomol for research purposes only. Not for diagnostic purposes or human use. It may not be resold or used to manufacture commercial products without written approval of Biomol GmbH.

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