|Aliases||TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515; ARNTL|
|Storage||4?; -20? for long term storage|
|Immunogen||Purified recombinant fragment of human ARNTL expressed in E. Coli.
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|WB||1/500 - 1/2000|
|IHC||1/200 - 1/1000|
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
|1. Chronobiol Int. 2007;24(5):783-92.
2. Mol Cell Biol. 2008 Oct;28(19):6056-65.
3. J Affect Disord. 2009 Sep;117(1-2):87-97.
Figure 1: Western blot analysis using ARNTL mouse mAb against ARBTL(AA: 1-310)-hIgGFc transfected HEK293 cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded human Spleen tissues using anti-ARNTL mouse mAb
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