Anti-ARNTL, clone 1C5

Art Nr.: Pro-30033, ProMab
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Entrez GeneID 406
Aliases TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515; ARNTL
Clone# 1C5
MW 68.7kDa
Host/Isotype Mouse IgG1
Storage 4?; -20? for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human ARNTL expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
1. Chronobiol Int. 2007;24(5):783-92.
2. Mol Cell Biol. 2008 Oct;28(19):6056-65.
3. J Affect Disord. 2009 Sep;117(1-2):87-97.
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Western Blot

Figure 1: Western blot analysis using ARNTL mouse mAb against ARBTL(AA: 1-310)-hIgGFc transfected HEK293 cell lysate.

Immunohistochemical analysis

Figure 2: Immunohistochemical analysis of paraffin-embedded human Spleen tissues using anti-ARNTL mouse mAb

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