Anti-ARNTL, clone 1C5

Art Nr.: Pro-30033, ProMab
Biomol GmbH
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22769 HAMBURG
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Specification
Entrez GeneID 406
Aliases TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515; ARNTL
Clone# 1C5
MW 68.7kDa
Host/Isotype Mouse IgG1
Storage 4?; -20? for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human ARNTL expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Application
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ICC N/A
FCM N/A
ELISA 1/10000
Description
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
References
1. Chronobiol Int. 2007;24(5):783-92.
2. Mol Cell Biol. 2008 Oct;28(19):6056-65.
3. J Affect Disord. 2009 Sep;117(1-2):87-97.
Seqence
1-310
Related Products

Western Blot

Figure 1: Western blot analysis using ARNTL mouse mAb against ARBTL(AA: 1-310)-hIgGFc transfected HEK293 cell lysate.

Immunohistochemical analysis

Figure 2: Immunohistochemical analysis of paraffin-embedded human Spleen tissues using anti-ARNTL mouse mAb


This product is offered by Biomol for research purposes only. Not for diagnostic purposes or human use. It may not be resold or used to manufacture commercial products without written approval of Biomol GmbH.

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