Cytokines are signaling proteins in cellular communication. While hormones are secreted from specific organs to the blood, and neurotransmitters are related to neural activity, the cytokines are a more diverse class of compounds in terms of origin and purpose. They are produced by a wide variety of hematopoietic and non-hematopoietic cell types and can have autocrine, paracrine and endocrine effects, sometimes strongly dependent on the presence of other chemicals. The cytokine family consists mainly of smaller, water-soluble proteins and glycoproteins with a mass between 8 and 30 kDa.
The term cytokine is used generically for interleukins
, growth factors
and similar extracellular proteinaceous ligands (lymphokines, monokines, interferons
, colony-stimulating factors
, immunomodulators, immunotransmitters, etc.).
Cytokines can be isolated from natural sources or are recombinant and produced in bacteria
or higher eukaryotic cells
. Wheras bacterially expressed ones lack post-translational modifications, the latter are glycoproteins. In many assays non-glycosylated cytokines show a similar activity as glycosylated ones, for some studies glycosylation is important.
Cytokine Product Line
, ORF Genetics
, and Humanzyme
produce more than 1000 cytokines, all available from Biomol .
At Biomol you find this extensive range of cytokines:
About 400 of Biomol\'s cytokines are presented in this pdf document
Cytokine and Ligand ELISA Kits
Biomol offers a selection of affordable and easy-to-use ELISA kits
for determination of concentration cytokines (and similar ligands).
Product Line Presentations
Biomol offers also thousands of antibodies
for the analysis of cytokines and similar ligands.
New: Cytokine antibodies for veterinary research
New: Antibodies raised against authentic human cytokines
Authentic Human Cytokines
Biomol offers a range of human cytokines, which have been recombinantly produced in human cell lines. They carry authentic glycosyslation making them more stable and active:
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HumaXPress Human Cell Line Expressed Cytokines
Kingfisher Cytokines for Veterinary Research
Kingfisher Biotech, Inc. is committed to accelerating basic veterinary research and human disease research done in animal models by developing and commercializing research reagents specific for a variety of species previously underserved in the commercial market:
(Cattle, Cow, Ox, Bull, Bos taurus)
(Dog, Canis lupus familiaris)
(Cock, Hen, Gallus gallus domesticus)
(Horse, Equus ferus caballus)
(Cat, Felis catus)
(Bunny, buck, doe, coney, Oryctolagus cuniculus)
(Pig, Porcine, Sus domestica)
(hen, poult, tom, stag, Meleagris gallopavo)