HERSTELLER

Cytokines


Cytokines are signaling proteins in cellular communication. While hormones are secreted from specific organs to the blood, and neurotransmitters are related to neural activity, the cytokines are a more diverse class of compounds in terms of origin and purpose. They are produced by a wide variety of hematopoietic and non-hematopoietic cell types and can have autocrine, paracrine and endocrine effects, sometimes strongly dependent on the presence of other chemicals. The cytokine family consists mainly of smaller, water-soluble proteins and glycoproteins with a mass between 8 and 30 kDa.


The term cytokine is used generically for interleukins, chemokines, growth factors, neurotrophins and similar extracellular proteinaceous ligands (lymphokines, monokines, interferons, colony-stimulating factors, immunomodulators, immunotransmitters, etc.).

Cytokines can be isolated from natural sources or are recombinant and produced in bacteria, yeast or higher eukaryotic cells. Wheras bacterially expressed ones lack post-translational modifications, the latter are glycoproteins. In many assays non-glycosylated cytokines show a similar activity as glycosylated ones, for some studies glycosylation is important.

Cytokine Product Line


Biomol, Imgenex, Kingfisher, ORF Genetics, BPS, USBio, AdipoGen, and Humanzyme produce more than 1000 cytokines, all available from Biomol .

At Biomol you find this extensive range of cytokines:
Cytokines produced in: Cytokines of this origin:

About 400 of Biomol\'s cytokines are presented in this pdf document (102 kB).

Cytokine and Ligand ELISA Kits


Biomol offers a selection of affordable and easy-to-use ELISA kits for determination of concentration cytokines (and similar ligands).

Product Line Presentations

Cytokine Antibodies


Biomol offers also thousands of antibodies for the analysis of cytokines and similar ligands.

New: Cytokine antibodies for veterinary research.

New: Antibodies raised against authentic human cytokines.

Authentic Human Cytokines


New: Biomol offers a range of human cytokines, which have been recombinantly produced in human cell lines. They carry authentic glycosyslation making them more stable and active:
More Info ...

HumaXPress Human Cell Line Expressed Cytokines


Kingfisher Cytokines for Veterinary Research


Kingfisher Biotech, Inc. is committed to accelerating basic veterinary research and human disease research done in animal models by developing and commercializing research reagents specific for a variety of species previously underserved in the commercial market:
Bovine (Cattle, Cow, Ox, Bull, Bos taurus)
Canine (Dog, Canis lupus familiaris)
Chicken (Cock, Hen, Gallus gallus domesticus)
Equine (Horse, Equus ferus caballus)
Feline (Cat, Felis catus)
Rabbit (Bunny, buck, doe, coney, Oryctolagus cuniculus)
Swine (Pig, Porcine, Sus domestica)
Turkey (hen, poult, tom, stag, Meleagris gallopavo)

Cytokine Search Engine


Biomol presents a search engine for finding cytokines:
Search and find Cytokines

Topical Cytokine News


Read up-to-date cytokine news at twitter.com/cytokines

New Authentic Human Cytokines


Human cell expressed recombinant humen cytokines with high activity, authentic folding, multimerisation and glycosylation. And very attractively priced. More ...



Pland Expressed Cytokines


Clean and glycosylated cytokines (very low endotoxin) expressed in plants (barley grain): bio-clean cytokines.



Order Info


Alphabetical Listing of Cytokines


4, A, B, C, E, F, G, H, I, K, L, M, N, O, P, R, S, T, V.

Cytokines by Origin:


A, B, C, E, F, G, H, I, K, L, M, N, O, P, R, S, T, V.

About 400 of Biomol\'s cytokines are presented in this pdf document (650 kB).

Alphabetical Listing of Important Cytokines


4-1BB Ligand
Activin A
Adiponectin (Acrp30)
AITRL
Angiopoietin-1
Angiopoietin-2
Angiopoietin-like Protein-3
Angiopoietin-like Protein-4
Apolipoprotein D (Apo-D)
Apolipoprotein J (Apo-J)
Artemin
BAFF (BLyS)
Betacellulin
Bone Morphogenetic Protein-2 (BMP-2)
Bone Morphogenetic Protein-4 (BMP-4)
Bone Morphogenetic Protein-6 (BMP-6)
Bone Morphogenetic Protein-7 (BMP-7)
Bone Morphogenetic Protein Receptor-1A (BMPR-1A)
Brain Derived Neurotrophic Factor (BDNF)
BRAK (CXCL14)
B-type Natriuretic Protein (BNP)
C-10 (CCL6)
Cardiotrophin-1
CD40 Ligand/TRAP (CD40L)
Ciliary Neurotrophic Factor (CNTF)
Clusterin
Complement C1q Tumor
Connective Tissue Growth Factor (CTGF)
Cytotoxic T-Lymphocyte Associated Antigen-4/Fc Chimera
Beta-Defensin-1 (BD-1)
Beta-Defensin-2 (BD-2)
Beta-Defensin-3 (BD-3)
Endocrine Gland Vascular Endothelial Growth Factor (EG-VEGF)
Endoglin
Endothelial Monocyte Activating Polypeptide II (EMAPII)
Eotaxin (CCL11)
Epidermal Growth Factor (EGF)
Epigen (EPGN)
Epiregulin (EREG)
Epithelial Neutrophil-Activating Protein-78 (CXCL5, ENA-78)
Epstein Barr Virus Induced 3
Erythropoietin
Erythropoietin alpha Fc/Chimera
Exodus-2 (CCL21)
Fibroblast Growth Factor-9 (FGF-9)
Fibroblast Growth Factor-19 (FGF-19)
Fibroblast Growth Factor-21 (FGF-21)
Fibroblast Growth Factor-22 (FGF-22)
Fibroblast Growth Factor-23 (FGF-23)
Fibroblast Growth Factor, acidic (FGF-acidic)
Fibroblast Growth Factor, basic (FGF-basic)
Flt3-Ligand
Follistatin (FST)
Fractalkine
Galectin-1 (Gal-1)
Galectin-3 (Gal-3)
Glial Derived Neurotrophic Factor (GDNF)
Glia Maturation Factor beta (GMF-beta)
Glia Maturation Factor gamma (GMF-gamma)
GM-CSF/IL-3 Fusion Protein (PIXY321)
Granulocyte Colony Stimulating Factor (G-CSF)
Granulocyte Machrophage Colony Stimulating Factor (GM-CSF)
GRO-alpha (CXCL1)
GRO-beta/MIP-2 (CXCL2)
GRO-gamma (CXCL3)
GRO/KC (CXCL1)
Growth and Differentiation Factor-5 (GDF-5)
Growth Hormone (GH)
Growth Hormone Antagonist (GH-A)
Growth Hormone Binding Protein (GHBP)
HCC-1 (CCL14)
Hepatocyte Growth Factor (HGF)
I-309 (CCL1)
Insulin
Insulin-Like Growth Factor-I (IGF-1)
Insulin-Like Growth Factor-II (IGF-2)
Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1)
Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3)
Insulin-Like Growth Factor Binding Protein-5 (IGFBP-5)
Insulin-Like Growth Factor Binding Protein-6 (IGFBP-6)
Interferon alpha (IFN-alpha)
Interferon alpha1 (IFN-alpha1)
Interferon alpha1a (IFN-alpha1a)
Interferon alpha1b (IFN-alpha1b)
Interferon alpha2a (IFN-alpha2a)
Interferon alpha2b (IFN-alpha2b)
Interferon beta1a (IFN-beta1a)
Interferon beta1b (IFN-beta1b)
Interferon gamma (IFN-gamma)
Interferon tau (IFN-tau)
Interferon Regulatory Factor-1 (IRF-1)
Interferon Regulatory Factor-2 (IRF-2)
Interferon Regulatory Factor-3 (IRF-3)
Interleukin-1 alpha (IL-1-alpha)
Interleukin-1 beta (IL-1-beta)
Interleukin-1 Receptor Antagonist (IL-1RA)
Interleukin-2 (IL-2)
Interleukin-3 (IL-3)
Interleukin-4 (IL-4)
Interleukin-5 (IL-5)
Interleukin-6 (IL-6)
Interleukin-7 (IL-7)
Interleukin-8 (CXCL8)
Interleukin-9 (IL-9)
Interleukin-10 (IL-10)
Interleukin-11 (IL-11)
Interleukin-12 (IL-12)
Interleukin-13 (IL-13)
Interleukin-15 (IL-15)
Interleukin-16 (IL-16)
Interleukin-17A (IL-17A)
Interleukin-18 (IL-18)
Interleukin-19 (IL-19)
Interleukin-20 (IL-20)
Interleukin-21 (IL-21)
Interleukin-22 (IL-22)
Interleukin-24 (IL-24)
Interleukin-27 (IL-27)
Interleukin-28A (IL-28A)
Interleukin-29 (IL-29)
Interleukin-31 (IL-31)
Interleukin-32 alpha (IL-32a)
Interleukin-33 (IL-33)
IP-10 (CXCL10)
I-TAC (CXCL11)
Keratinocyte Growth Factor (KGF)
Keratinocyte Growth Factor-2 (KGF-2)
Leptin
Leptin Binding Domain (Leptin-BD)
Leptin Triple Antagonist (Leptin-tA)
Leptin Quadruple Antagonist (Leptin-qA)
LeukinFeron
Leukemia Inhibitory Factor (LIF)
Leukocyte Function Associated Antigen-3 Fusion Protein (LFA-3)
Lymphotactin
Macrophage Colony Stimulating Factor (M-CSF)
Macrophage Inflammatory Protein-1 alpha (CCL3)
Macrophage Inflammatory Protein-1 beta (CCL4)
Macrophage Inflammatory Protein-3 alpha (CCL20)
Macrophage Inflammatory Protein-3 beta (CCL19)
Macrophage Inflammatory Protein-4 (CCL18)
Macrophage Inflammatory Protein-5 (CCL15, MIP-5)
Macrophage Migration Inhibitory Factor (MIF)
Melanoma Inhibitory Activity Protein (MIA)
Melanoma Inhibitory Activity 2 (MIA2)
Midkine
MIG (CXCL9)
Monocyte Chemotactic Protein-1/MCAF (CCL2, MCP-1/MCAF)
Monocyte Chemotactic Protein-1 (CCL2, MCP-1)
Monocyte Chemotactic Protein-2 (CCL8, MCP-2)
Monocyte Chemotactic Protein-3 (CCL7, MCP-3)
Monocyte Chemotactic Protein-4 (CCL13, MCP-4)
Myostatin
Myostatin Propeptide (GDF-8)
Nerve Growth Factor beta (NGF)
Neuregulin-1/Herugulin-1 (NRG1)
Neuroglobin
Neurotrophin-3
Neurotrophin-4
Neutrophil Activating Protein-2 (CXCL7)
Noggin (NOG)
Omentin
Oncostatin M (OSM)
Osteoclast Stimulating Factor-1
Osteopontin (Secreted Phosphoprotein-1)
Osteoprotegerin (OPG)
Otoraplin
PEDF (Pigment Epithelium Derived Factor)
Periostin (OSF-2)
Pituitary Growth Hormone-20K
Placenta Growth Factor-1 (PLGF-1)
Placenta Growth Factor-2 (PLGF-2)
Placental Growth Hormone-20K
Placental Lactogen
Placental-Corr Growth Hormone
Platelet Derived Growth Factor-A (PDGF-A)
Platelet Derived Growth Factor-AA (PDGF-AA)
Platelet Derived Growth Factor-AB (PDGF-AB)
Platelet Derived Growth Factor-B (PDGF-B)
Platelet Derived Growth Factor-BB (PDGF-BB)
Platelet Factor-4 (CXCL4, PF-4)
Pleiotrophin
Progranulin
Prolactin
Prolactin Antagonist
Prolactin Receptor
Prolactin Soluble Receptor
Pro-Nerve Growth Factor (pro-NGF)
RANK Ligand
RANTES (CCL5)
RELM-alpha
RELM-beta
RELM-gamma
Resistin
Retinol Binding Protein-4 (RBP-4)
Sonic Hedgehog (SHH)
Stem Cell Factor (SCF)
Stromal Cell-Derived Factor-1 alpha (CXCL12, SDF-1a)
Stromal Cell-Derived Factor-1 beta (CXCL12, SDF1b)
Thrombopoietin (TPO)
Thymic Stromal Lymphopoietin (TSLP)
TNF-Related Apoptosis Inducing Ligand/Apo2L (TRAIL)
TNFRSF17 (B-Cell Maturation Antigen)
Transforming Growth Factor beta1 (TGF-b1)
Transforming Growth Factor beta3 (TGF-b3)
Trefoil Factor-1 (TFF1)
Trefoil Factor-2 (TFF2)
Trefoil Factor-3 (TFF3)
Tumor Necrosis Factor alpha (TNF-a)
Tumor Necrosis Factor beta (TNF-b)
Tumor Necrosis Factor Receptor Fusion Protein (TNFR)
Soluble Tumor Necrosis Factor Receptor Inhibitor (sTNFRI)
Vascular Endothelial Growth Factor (VEGF)
Vascular Endothelial Growth Factor-121 (VEGF-121)
Vascular Endothelial Growth Factor-164 (VEGF-164)
Vascular Endothelial Growth Factor-165 (VEGF-165)
Vascular Endothelial Growth Factor-B (VEGF-B)
Vascular Endothelial Growth Factor-C (VEGF-C)
Vascular Endothelial Growth Factor-E (VEGF-E)
Vascular Endothelial Growth Factor Related Protein (VEGF-C)
Vascular Endothelial Growth Factor Inhibitor (VEGFI)
Vaspin
Visfatin

New additions to Biomol\'s cytokine product line in October 2009

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