Apoptosis is the process of programmed cell death that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, loss of cell membrane asymmetry and attachment, change in mitochondrial potential, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation.

Detection of Apoptosis

Charecteristic cell changes can be used to monitor apoptosis:

Novel Apoptosis Detection Assays

pSIVA, the first reversible probe for detecting phosphatidylserine (PS) exposure on plasma membranes.

NIR-FLIVO™: Powerful new reagents for near infrared imaging of apoptosis in live animals.

Apotosis Detection Assays

FLICA™ in vitro Apoptosis Detection Kits

Image Apoptosis in vivo Non-Invasively

NIR-FLIVO in vivo Apoptosis Kits

pSIVA: Polarity Sensitive Indicator of Viability & Apoptosis

Annexin V Apoptosis Detection Kit

Reagents and Assay Kits for Cell Apoptosis and Cytotoxicity

Cell Based Assays

Monitor Apoptosis in Real Time in vitro

Assess Neurodegeneration in vivo