- Search results for Cay13748
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6 products were found matching "Cay13748"!
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Item number: Cay13874-5
Tenofovir is an analog of adenosine monophosphate that has antiviral activity. It is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Tenofovir diphosphate is a weak inhibitor of mammalian...
Keywords: | (R)-PMPA, GS-1275, GS-1278, TDF, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid |
Application: | Antiviral, Reverse transcriptase inhibitor |
CAS | 147127-20-6 |
MW: | 287.2 D |
From 109.00€
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Item number: Cay13784-1
Histone H3.3 is a nuclear protein and a replication-independent member of the histone H3 family that has a role in nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped...
Keywords: | H3.3A, H3.3B, H3F3A, H3F3B |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | chicken, ovine, Drosophila, equine, human, murine, opossum |
442.00€
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Item number: Cay14378-5
BB-22 (Cay-14099) is an analog of the potent synthetic cannabinoid, JWH 018 (Cay-10900) that is structurally similar to PB-22 (Cay-14096) and its derivative, 5-fluoro PB-22 (Cay-14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22 3-carboxyindole...
Keywords: | 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid |
Application: | Analytical reference standard, expected BB-22 metabolite (serum/urine ) |
CAS | 858515-71-6 |
MW: | 257.3 D |
From 158.00€
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COVID-19 Research
Item number: Cay14837-10
Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease, Ki = 15 nM), tryptase (a mast cell protease, Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 µM). In a mouse model of allergic asthma, a dose of 300 mg/kg...
Keywords: | Coahibitor, FUT 175, Nafamastat, 4-[(aminoiminomethyl)amino]-6-(aminoiminomethyl)-2-naphthalenyl ester-benzoic acid,... |
Application: | Serine protease inhibitor |
CAS | 82956-11-4 |
MW: | 539.6 D |
From 50.00€
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Item number: Cay17348-1
Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at...
Keywords: | Adiuretin, DDAVP,... |
Application: | Vasopressin V1a, V1b, V2 receptor agonist |
MW: | 1069.2 D |
From 60.00€
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Item number: Cay18374-5
L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50s = 5, 9, and 5 µM, respectively). It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA,...
Keywords: | 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone |
Application: | DNA ligase I, III, IV inhibitor |
CAS | 64232-83-3 |
MW: | 246.3 D |
From 115.00€
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