- Search results for Cay16851
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13 products were found matching "Cay16851"!
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Item number: Cay16685-1
Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Cay-16680) and bimatoprost (17-phenyl trinor Prostaglandin F2alpha ethyl amide, Cay-16820), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor. Based on classical...
Keywords: | Maxeyprost, Unoprostone N-ethyl amide, N-ethyl-9alpha,11alpha-dihydroxy-15-oxo-20a,20b-dihomoprost-5-en-1-amide |
Application: | Bioactive lipid assays |
CAS | 511229-72-4 |
MW: | 409.6 D |
From 319.00€
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Item number: Cay16885-1
Evodiamine is a natural indole alkaloid found in the fruits of Wu Zhu Yu, a plant used in traditional Chinese medicine. Studies involving evodiamine have demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions. It can act as an aryl hydrocarbon antagonist (Ki = 28 nM), activator...
Keywords: | D-Evodiamine, 8,13,13bS,14-tetrahydro-14-methyl-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one |
Application: | Quinazoline alkaloid, AhR antagonist, K05222 activator |
CAS | 518-17-2 |
MW: | 303.4 D |
From 50.00€
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Item number: Cay11685-1
Bavachin is a flavonoid first isolated from seeds of P. corylifolia. It is a phytoestrogen that activates the estrogen receptors ERalpha and ERbeta (EC50s = 320 and 680 nM, respectively). Through this action, bavachin stimulates osteoblast proliferation and differentiation and prevents bone loss following...
Keywords: | Corylifolin, (2S)-2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
Application: | Phytoestrogen, Estrogen receptor agonist |
CAS | 19879-32-4 |
MW: | 324.4 D |
From 60.00€
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Item number: Cay16854-1
8(Z),14(Z)-Eicosadienoic Acid is an omega-8 C20:2 fatty acid. The presence of 8(Z),14(Z)-eicosadienoic acid has been detected in human milk at a level of 0.19% (weight % total fatty acids). Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators. The...
Keywords: | (8Z,14Z)-eicosadienoic acid |
Application: | Bioactive lipid studies |
CAS | 135498-07-6 |
MW: | 308.5 D |
From 114.00€
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Item number: Cay16385-1
alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
Keywords: | alpha-bungarotoxin, trifluoroacetate salt |
Application: | Irreversible nicotinic acetylcholine receptor blocker |
MW: | 7984.1 D |
319.00€
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Item number: Cay16985-1
Rp-Cyclic AMPS (Rp-cAMPS) is a non-hydrolyzable phosphorothioate analog of cAMP. It is a competitive inhibitor of cAMP-dependent protein kinases I and II (IC50s = 12.5 and 4.5 µM, respectively). Rp-cAMPS is not hydrolyzed by bovine heart cAMP phosphodiesterase but can be hydrolyzed by yeast phosphodiesterase. It is...
Keywords: | Rp-cAMPS, cyclic 3',5'-[hydrogen (R)-phosphorothioate] adenosine, triethylammonium salt |
Application: | Competitive cAMP-dependent protein kinases I / II inhibitor |
CAS | 151837-09-1 |
MW: | 446.5 D |
From 105.00€
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Item number: Cay16835-1
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It...
Keywords: | 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid |
Application: | EP4 receptor activator |
CAS | 64054-40-6 |
MW: | 341.5 D |
From 96.00€
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Item number: Cay16285-1
TAK-632 is a slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively). It demonstrates 14-1,200-fold selectivity for Raf over a panel of 26 different kinases. TAK-632 shows significant antiproliferative activity against mutated B-Raf or...
Keywords: | N-[5-[[7-cyano-2-[(cyclopropylcarbonyl)amino]-6-benzothiazolyl]oxy]-2-fluorophenyl]-3-(trifluoromethyl)-benzeneacetamide |
Application: | RAF inhibitor |
CAS | 1228591-30-7 |
MW: | 554.5 D |
From 43.00€
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Item number: Cay16825-1
15(R)-17-phenyl trinor Prostaglandin F2alpha isopropyl ester (15(R)-17-phenyl trinor PGF2alpha isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (beta) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2alpha isopropyl ester is a...
Keywords: | 15(R)-17-phenyl trinor PGF2alpha isopropyl ester, 15(R)-Bimatoprost isopropyl ester, 15-epi Bimatoprost isopropyl ester,... |
Application: | Bioactive lipid assays |
CAS | 130273-87-9 |
MW: | 430.6 D |
From 98.00€
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Item number: Cay16485-1
1-thio-beta-D-Glucose is an analog of beta-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including the thiol-Michael addition reaction and polymerization. 1-thio-beta-D-Glucose can be labeled with technetium-99m for analytical and...
Keywords: | Click Tag(TM) 1-Thio-beta-D-glucose, 1-thio-beta-D-glucopyranose, monosodium salt |
Application: | Click chemistry, glucose oxidase substrate |
CAS | 10593-29-0 |
MW: | 218.2 D |
From 54.00€
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Item number: Cay16895-1
A number of 17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have been approved for the treatment of glaucoma. Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side...
Keywords: | 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2alpha,... |
Application: | Bioactive lipid assays |
CAS | 294856-01-2 |
MW: | 458.5 D |
From 94.00€
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Item number: Cay16785-1
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) was recently introduced as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group of fluprostenol produces 15-keto fluprostenol....
Keywords: | (±)15-oxo-9alpha,11alpha-dihydroxy-16,16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
MW: | 456.5 D |
From 84.00€
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