Let BIOMOL be your virtual organic chemistry support group for the production of different molecules.
We can provide you with a cost effective means of
carrying out your project in a timely and efficient manner.
All partners of our network maintain fully staffed, state of the art laboratories and are capable
of performing modern organic synthesis at the milligram to the kilogram scale.
The most important procedures that are carried out are:
· Acetylations by acetyl chloride and acetic acid anhydride
· Alkylations by alkyl halides and alkyl sulfates
· Carboxylic ester condensation
· Catalytic hydrogenations up to 5 bar (1 L autoklav)
· Catalytic reductions by hydrogen
· Chlorinations by thionyl chloride
· Cleavage of ethers by BBr3
· Diazotizations and Sandmeyer reactions
· Eschweiler-Clarke methylations
· Esterifications and saponifications
· Fluorinations by different fluorinating reagents
· Formations of ethers by different methods (Williamson, Mitsunobu)
· Friedel-Crafts alkylations and acylations
· Gabriel synthesis
· Haloform reactions
· Halogenations and halogen exchange reactions
· Hydroborations by 9-BBN, borane-THF and borane-amine complexes
· Hydroxymethylations by formaldehyde
· Isolations of natural substances
· Ketone and aldehyde condensation reactions
· Knoevenagel condensations
· Michael reactions
· Nitrations of aromatic rings
· Nucleophilic substitution reactions
· Oxidations by peracids, H2O2, nitric acid and others
· Perkin reaction
· Purifications of chemicals for special applications
· Reactions at low temperatures (up to -78°C)
· Reactions using hydrogen chloride
· Reactions in an inert gas atmosphere
· Reductions by metal hydrides
· Reductions by sodium metal
· Reductive aminations
· Separation of enantiomers
· Silylations
· Sulfonations and chlorosulfonations
· Synthesis of deuterated compounds
· Synthesis of carboxylic acid chlorides by PCl5, PCl3 or SOCl2
· Synthesis elaboration for new compounds
· Synthesis of heterocyclic compound by various methods
· Synthesis of indole derivatives
· Synthesis of protected and unnatural amino acids
· Synthesis of metal salts of inorganic or organic acids
· Synthesis using organometallic compounds
(Grignard- and organolithium compounds)
· Tailor made solutions and mixtures
· Vilsmeier reactions
· Wittig- and Wittig-Horner reactions
· Wolff-Kishner reductions
and many many more ......
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