5 products were found matching "Cay13332"!

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(S)-Glycyl-H-1152 (hydrochloride)
(S)-Glycyl-H-1152 (hydrochloride)

Item number: Cay13332-500

Two Rho-associated kinases (ROCK), ROCK1 and ROCK2, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. Glycyl-H-1152 is a selective and potent...
Keywords: Rho Kinase Inhibitor IV,...
Application: ROCK inhibitor
CAS 913844-45-8
MW: 449.4 D
From 125.00€ *
Review
CGP 57380
CGP 57380

Item number: Cay13322-5

CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1) in vitro (IC50 = 2.2 µM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. It blocks the phosphorylation of eIF4E in response to TNF-alpha, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 =...
Keywords: MNK1 Inhibitor, N3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
Application: MAPK-interacting kinase 1 inhibitor
CAS 522629-08-9
MW: 244.2 D
From 60.00€ *
Review
2-Acetyl-5-tetrahydroxybutyl Imidazole
2-Acetyl-5-tetrahydroxybutyl Imidazole

Item number: Cay13222-5

2-Acetyl-5-tetrahydroxybutyl imidazole (THI) is an inhibitor of sphingosine-1-phosphate (S1P) lyase in vivo. THI is not active at S1P lyase in cell-free or cell-based assays but is converted to A6770 in vivo, which is subsequently activated by phosphorylation. In mice, THI (50 µg/ml in drinking water) increases S1P...
Keywords: 2-Acetyl-4-tetrahydroxybutyl Imidazole, 2-ATHBI, THI, 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone
Application: S1P lyase inhibitor
CAS 94944-70-4
MW: 230.2 D
From 86.00€ *
Review
Delta2-trans-Hexadecenoic Acid
Delta2-trans-Hexadecenoic Acid

Item number: Cay11132-5

Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues. Delta2-trans-Hexadecenoic acid is an intermediate formed in the beta-oxidation of palmitic acid. In a model meant to simulate gastric ulceration,...
Keywords: 2E-hexadecenoic acid
Application: Bioactive lipid assays
CAS 929-79-3
MW: 254.4 D
From 74.00€ *
Review
Fumagillin
Fumagillin

Item number: Cay11332-5

Fumagillin is a fungal metabolite that has been found in A. fumigatus and has diverse biological activities. It inhibits methionyl aminopeptidase 2 (METAP2, IC50 = 10 nM). Fumagillin (10 ng/ml) inhibits tube formation in a rat blood vessel organ culture assay. It inhibits E. cuniculi replication in isolated rabbit...
Keywords: Amebacilin, NSC 9168, 2E,4E,6E,8E-decatetraenedioic acid,...
Application: Angiogenesis inhibitor, metabolic studies
CAS 23110-15-8
MW: 458.6 D
From 129.00€ *
Review