- Search results for Cay10215
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6 products were found matching "Cay10215"!
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Item number: Cay10215-500
The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and...
Keywords: | Isopropyl Dodecylfluorophosphonate, P-dodecyl-phosphonofluoridic acid, 1-methylethyl ester |
Application: | MGL inhibitor |
CAS | 615250-02-7 |
MW: | 294.4 D |
From 77.00€
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Item number: Cay11021-5
CHS-828 is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor (IC50 = + levels in, and is cytotoxic to, HeLa cervical cancer cells. It decreases ATP levels in C666-1 nasopharyngeal and FaDu head and neck squamous cell carcinoma (HNSCC) cells in a time-dependent manner when used at concentrations of 10 and 20...
Keywords: | GMX 1778, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-guanidine |
Application: | Apoptosis inducer |
CAS | 200484-11-3 |
MW: | 371.9 D |
From 98.00€
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Item number: Cay10021-5
Clioquinol is a metal-chelating antimicrobial agent with neuroprotective properties. It inhibits the growth of A. fumigatus with MIC values of 1, >32, 8, and 16 µg/ml in media containing no metal, iron, zinc, and copper, respectively. Clioquinol (37 mg/kg) decreases neuronal loss in the substantia nigra pars...
Keywords: | Iodochlorohydroxyquin, NSC 3531, NSC 74938, 5-chloro-7-iodo-8-quinolinol |
Application: | Antifungal, Amebicide, Metal-chelating antimicrobial agent, Neuroprotective agent |
CAS | 130-26-7 |
MW: | 305.5 D |
From 34.00€
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Item number: Cay10210-5
Prostaglandin A2 (PGA2) is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. At a 25 µM concentration, PGA2 blocks the cell cycle...
Keywords: | Medullin, PGA2, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 13345-50-1 |
MW: | 334.5 D |
From 43.00€
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Item number: Cay10217-5
24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRalpha and LXRbeta...
Keywords: | 24-Epicerebrosterol, cholest-5-ene-3beta,24R-diol |
Application: | LXR alpha / beta agonist |
CAS | 27460-26-0 |
MW: | 402.7 D |
From 66.00€
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Item number: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
Keywords: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
Application: | PARP1 / PARP2 inhibitor |
CAS | 763113-22-0 |
MW: | 434.5 D |
From 66.00€
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