15 products were found matching "6664-1"!

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Mozavaptan (hydrochloride)
Mozavaptan (hydrochloride)

Item number: Cay16664-10

Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,...
Application: Arginine vasopressin receptor 2 (AVPR2) antagonist
CAS 138470-70-9
MW: 464 D
From 48.00€ *
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3'-Ethoxy Spinosyn L
3'-Ethoxy Spinosyn L

Item number: Cay26664-1

3'-Ethoxy spinosyn L is a minor component of the insecticide spinetoram (Cay-26623). Formulations containing 3'-ethoxy spinosyn L have been used as insecticides.Formal Name:...
Keywords: Spinetoram L,...
Application: Minor spinetoram component
CAS 187166-15-0
MW: 760 D
From 265.00€ *
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E3 Ligase Ligand 2
E3 Ligase Ligand 2

Item number: Cay36664-1

E3 ligase ligand 2 is an active metabolite of thalidomide (Cay-14610) and an intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs) containing thalidomide, a ligand for the E3 ubiquitin ligase cereblon (CRBN), used in targeted protein degradation. E3 ligase ligand 2 is formed from thalidomide via...
Keywords: 4-hydroxy Thalidomide, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione
Application: Thalidomide active metabolite, PROTAC synthetic intermediate
CAS 5054-59-1
MW: 274.2 D
From 40.00€ *
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Anti-CAND1
Anti-CAND1

Item number: E-AB-66264.120

This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F...
Keywords: Anti-CAND1, Anti-KIAA0829, Anti-p120 CAND1, Anti-TBP-interacting protein 120A, Anti-TBP-interacting protein of 120 kDa A,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
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Anti-(KO Validated) CHRAC1
Anti-(KO Validated) CHRAC1

Item number: E-AB-66364.120

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. Protein function: Forms a complex with DNA polymerase epsilon...
Keywords: Anti-CHRAC1, Anti-CHRAC-1, Anti-CHRAC15, Anti-CHRAC-15, Anti-HuCHRAC15, Anti-DNA polymerase epsilon subunit p15,...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 218.00€ *
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Anti-TPCN1
Anti-TPCN1

Item number: E-AB-66604.120

Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]). Protein function: Nicotinic acid adenine dinucleotide phosphate (NAADP)...
Keywords: Anti-TPCN1, Anti-KIAA1169, Anti-Two pore calcium channel protein 1, Anti-Voltage-dependent calcium channel protein TPC1,...
Application: WB
Host: Rabbit
Species reactivity: mouse, rat
From 198.00€ *
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Anti-PPIL4
Anti-PPIL4

Item number: E-AB-66624.120

This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Protein function: PPIases accelerate the folding of proteins....
Keywords: Anti-PPIL4, Anti-PPIase, EC=5.2.1.8, Anti-Rotamase PPIL4, Anti-Cyclophilin-like protein PPIL4, Anti-Peptidyl-prolyl...
Application: IF
Host: Rabbit
Species reactivity: human
From 198.00€ *
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Anti-HEY1
Anti-HEY1

Item number: E-AB-66694.120

This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for...
Keywords: Anti-HEY1, Anti-HRT-1, Anti-CHF-2, Anti-hHRT1, Anti-HESR-1, Anti-BHLHB31, Anti-bHLHb31, Anti-HES-related repressor protein...
Application: IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
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Anti-(KO Validated) HSPB1
Anti-(KO Validated) HSPB1

Item number: E-AB-66764.120

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important...
Keywords: Anti-HspB1, Anti-HSP27, Anti-HSPB1, Anti-SRP27, Anti-HSP 27, Anti-28 kDa heat shock protein, Anti-Heat shock 27 kDa...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 218.00€ *
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Anti-NR5A2
Anti-NR5A2

Item number: E-AB-66964.120

The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of...
Keywords: Anti-B1F, Anti-hB1F, Anti-NR5A2, Anti-LRH-1, Anti-B1-binding factor, Anti-Liver receptor homolog 1, Anti-CYP7A...
Application: IHC
Host: Rabbit
Species reactivity: human
From 198.00€ *
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Streptimidone
Streptimidone

Item number: Cay29984-2.5

Streptimidone is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits protein synthesis in a cell-free assay when used at a concentration of 50 µg/ml. It reduces tumor growth in H.S. No. 1 human sarcoma and H.Ep. No. 3 human epidermoid carcinoma rat xenograft...
Keywords: Ao58A, NSC 66645, 4-[(2R,5S,6E)-2-hydroxy-5,7-dimethyl-4-oxo-6,8-nonadien-1-yl]-2,6-piperidinedione
Application: Bioactive bacterial metabolite
CAS 738-72-7
MW: 293.4 D
From 239.00€ *
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Anti-ANT1/ANT2/ANT3/ANT4
Anti-ANT1/ANT2/ANT3/ANT4

Item number: E-AB-66640.120

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in...
Keywords: Anti-ANT1, Anti-ANT 1, Anti-SLC25A4, Anti-ADP/ATP translocase 1, Anti-ADP,ATP carrier protein 1, Anti-Adenine nucleotide...
Application: WB
Host: Rabbit
Species reactivity: mouse, rat
From 198.00€ *
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