- Search results for 2519-1
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7 products were found matching "2519-1"!
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Item number: E-AB-52519.120
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of...
Keywords: | Anti-MICU1, Anti-Hom s 4, Anti-ara CALC, Anti-Atopy-related autoantigen CALC, Anti-Calcium uptake protein 1,... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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Item number: Cay21519-10
ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).Formal Name:...
Keywords: | N-[2-(cyclopentylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide, monohydrochloride |
Application: | IDH1 (R132H mutant ) inhibitor |
CAS | 1355327-02-4 |
MW: | 521 D |
From 53.00€
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Item number: Cay25119-1
Delta2-Avermectin B1a is a degradation product formed by the reversible base-catalyzed isomerization of ivermectin B1a (Cay-18768). It is less active than ivermectin against T. urticae (LC90s = 0.23 and 0.038 ppm, respectively).Molecular Formula: C48H72O14. Formula Weight: 873.1. Purity: >95%. Formulation: (Request...
Application: | Degradation product |
MW: | 873.1 D |
From 488.00€
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Item number: Cay25197-1
Didymin is a flavonoid that has been found in citrus fruits with diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cell death and increases superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) activity in SH-SY5Y cells...
Keywords: | (2S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-be... |
Application: | Bioactive flavonoid |
CAS | 14259-47-3 |
MW: | 594.6 D |
From 60.00€
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Item number: Cay25198-1
Isosakuranetin is a flavanone that has been found in Citrus species and has diverse biological activities. It inhibits calcium uptake induced by pregnenolone sulfate (PregS, Cay-21004) in HEK293 cells expressing mouse transient receptor potential melastatin 3 (TRPM3, IC50 = 50 nM). Isosakuranetin is selective for...
Keywords: | (2S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Application: | Bioactive flavanone |
CAS | 480-43-3 |
MW: | 286.3 D |
From 189.00€
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Item number: Cay25199-1
Senkyunolide A is a phthalide originally isolated from celery seed essential oil that has cytoprotective and antiproliferative activities. It protects against cell injury induced by corticosterone in PC12 cells in a time-dependent manner when used at concentrations ranging from 0.125 to 0.5 mg/ml and reduces...
Keywords: | (-)-Sedanenolide, (S)-Sedanenolide, (3S)-3-butyl-4,5-dihydro-1(3H)-isobenzofuranone |
Application: | Cytoprotective, antiproliferative phthalide |
CAS | 63038-10-8 |
MW: | 192.3 D |
From 48.00€
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Item number: Cay32519-1
Simurosertib is an inhibitor of cell division cycle 7 (Cdc7) kinase (IC50 = 0.26 nM). It is selective for Cdc7 over cyclin-dependent kinase 2 (Cdk2) and Rho-associated kinase 1 (ROCK1, IC50s = 6,300 and 430 nM, respectively). It inhibits phosphorylation of DNA replication licensing factor MCM2 in HeLa cells (IC50 =...
Keywords: | TAK-931, 2-(2S)-1-azabicyclo[2.2.2]oct-2-yl-6-(3-methyl-1H-pyrazol-4-yl)-thieno[3,2-d]pyrimidin-4(3H)-one |
Application: | Cdc7 kinase inhibitor |
CAS | 1330782-76-7 |
MW: | 341.4 D |
From 60.00€
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