- Search results for Cay10004985
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2 products were found matching "Cay10004985"!
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Item number: Cay10004985-5
Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 is a nutlin-3 analog which contains chlorine substituents at the 3 and 4 positions on two of the phenyl rings rather than a single 4-chloro as seen in nutlin-3. At high...
Keywords: | 4-[4,5-bis(3,4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carboxyl]-piperazin-2-one |
Application: | Nutlin-3 analog |
CAS | 1207480-88-3 |
MW: | 650.4 D |
From 85.00€
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Item number: Cay10498-5
HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM. It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...
Keywords: | B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid |
Application: | Reversible autotaxin inhibitor |
CAS | 1229652-21-4 |
MW: | 463.3 D |
From 97.00€
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