Anti-USP37

Anti-USP37
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-927A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A300-927A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during... more
Product information "Anti-USP37"
Protein function: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'- linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). [The UniProt Consortium]
Keywords: Anti-USP37, Anti-KIAA1594, EC=3.4.19.12, Anti-Ubiquitin thioesterase 37, Anti-Deubiquitinating enzyme 37, Anti-Ubiquitin carboxyl-terminal hydrolase 37, Anti-Ubiquitin-specific-processing protease 37
Supplier: Bethyl Laboratories
Supplier-Nr: A300-927A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A300-927A maps to a region between residue 930 and the C-terminus (residue 979) of human Ubiquitin Specific Peptidase 37 using the numbering given in entry NP_065986.1 (GeneID 57695).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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