4 products were found matching "Cay10011190-25"!

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Elesclomol
Elesclomol

Item number: Cay10011192-5

Elesclomol is an inducer of apoptosis and a copper ionophore. It induces the production of reactive oxygen species (ROS) and increases oxidative stress response gene expression in Ramos (RA 1) B cell lymphoma cells when used at a concentration of 500 nM. Elesclomol (100 nM) disrupts the mitochondrial membrane...
Keywords: NSC 174939, STA 4783, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide]-propanedioic acid
Application: Antitumor agent, apoptosis inducer
CAS 488832-69-5
MW: 400.5 D
From 84.00€ *
Review
SIRT1 (human, recombinant)
SIRT1 (human, recombinant)

Item number: Cay10011190-100

The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Keywords: hSIR2, SIR2L1, hSIRT1, 75SirT1, SIR2-like protein 1, SirtT1 75 kDa fragment, Regulatory protein SIR2 homolog 1,...
Application: Enzyme activity
MW: 89,2 kD
642.00€ *
Review
Terbinafine (hydrochloride)
Terbinafine (hydrochloride)

Item number: Cay10011619-250

Terbinafine is a broad-spectrum antifungal agent that has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 µg/ml). It selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 µM,...
Keywords: N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine, monohydrochloride
Application: Antifungal compound, Ergosterol biosynthesis inhibitor
CAS 78628-80-5
MW: 327.9 D
From 98.00€ *
Review
LDL Uptake Cell-Based Assay Kit
LDL Uptake Cell-Based Assay Kit

Item number: Cay10011125-1

Low-density lipoproteins (LDL) is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL is taken up by hepatic and extrahepatic tissues through LDL receptor-mediated endocytosis where it is internalized and degraded to free cholesterol and amino acids. Uptake of...
Keywords: Low-Density Lipoprotein Uptake
Application: FC, fluorescence
554.00€ *
Review