6 products were found matching "Cay10215"!

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IDFP
IDFP

Item number: Cay10215-500

The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and...
Keywords: Isopropyl Dodecylfluorophosphonate, P-dodecyl-phosphonofluoridic acid, 1-methylethyl ester
Application: MGL inhibitor
CAS 615250-02-7
MW: 294.4 D
From 77.00€ *
Review
CHS-828
CHS-828

Item number: Cay11021-5

CHS-828 is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor (IC50 = + levels in, and is cytotoxic to, HeLa cervical cancer cells. It decreases ATP levels in C666-1 nasopharyngeal and FaDu head and neck squamous cell carcinoma (HNSCC) cells in a time-dependent manner when used at concentrations of 10 and 20...
Keywords: GMX 1778, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-guanidine
Application: Apoptosis inducer
CAS 200484-11-3
MW: 371.9 D
From 98.00€ *
Review
Clioquinol
Clioquinol

Item number: Cay10021-5

Clioquinol is a metal-chelating antimicrobial agent with neuroprotective properties. It inhibits the growth of A. fumigatus with MIC values of 1, >32, 8, and 16 µg/ml in media containing no metal, iron, zinc, and copper, respectively. Clioquinol (37 mg/kg) decreases neuronal loss in the substantia nigra pars...
Keywords: Iodochlorohydroxyquin, NSC 3531, NSC 74938, 5-chloro-7-iodo-8-quinolinol
Application: Antifungal, Amebicide, Metal-chelating antimicrobial agent, Neuroprotective agent
CAS 130-26-7
MW: 305.5 D
From 34.00€ *
Review
Prostaglandin A2
Prostaglandin A2

Item number: Cay10210-5

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH...
Keywords: Medullin, PGA2, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 13345-50-1
MW: 334.5 D
From 43.00€ *
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24(R)-hydroxy Cholesterol
24(R)-hydroxy Cholesterol

Item number: Cay10217-5

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRalpha and LXRbeta...
Keywords: 24-Epicerebrosterol, cholest-5-ene-3beta,24R-diol
Application: LXR alpha / beta agonist
CAS 27460-26-0
MW: 402.7 D
From 66.00€ *
Review
Olaparib
Olaparib

Item number: Cay10621-5

Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
Keywords: AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
Application: PARP1 / PARP2 inhibitor
CAS 763113-22-0
MW: 434.5 D
From 66.00€ *
Review