SCF (human):Fc (human) (rec.) (non-lytic)

SCF (human):Fc (human) (rec.) (non-lytic)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-220SCF-C050 50 µg - -

3 - 9 business days*

314.00€
 
The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of... more
Product information "SCF (human):Fc (human) (rec.) (non-lytic)"
The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
Keywords: MGF, SCF, KITLG, sKITLG, Kit ligand, c-Kit ligand, Stem cell factor, Soluble KIT ligand, Mast cell growth factor
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-220SCF

Properties

Application: Bioassays
Conjugate: No
Host: Hamster cells
Species reactivity: human
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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