Biomol offers a comprehensive selection of antibodies for detection of cell cycle regulating proteins.
CDKs with their Regulator Protein, Cyclin or Other.
Cyclin Y is a recently identified member of the cyclin family of proteins which function as regulators of cyclin dependent kinases. It was identified as a protein that interacts with PFTK1, a factor that shares limited homology to CDKs, but functions as a CDK by regulating cell cycle progression and cell proliferation. The binding of cyclin Y to PFTK1 enhances PFTK1 kinase activity and influences its intracellular location. Cyclin Y is also known as cyclin fold protein 1, cyclin box protein 1, CCNY, CBCP1, and CFP1.
Cyclin and CDK used in Cell Cycle
More Related Proteins
ORC (Origin Recognition Complex)
MCM (Mini-Chromosome Maintenance complex)
Beyond Cell Cycle
Cyclin dependent kinases (CDKs) and their associated cyclin partners have long been recognized as complexes that play an integral role in the progression of the cell cycle. Recently, the well established role of the CDK/cyclin complexes has been broadened, and current studies show that an atypical group of CDK/cyclin complexes are also directly involved in activities such as transcription, translation, and mRNA processing. The transcriptional regulating cyclins include cyclin C, H, K, L1, L2, T1, and T2 which associate with CDK8, -7, -9, and -11; the complexes formed by these factors appear to be involved in distinct aspects of transcription and splicing:
Loyer, P., Trembley, J. H., Katona, R., Kidd, V. J., & Lahti, J. M. (2005). Role of CDK/cyclin complexes in transcription and RNA splicing. Cell Signal., 17, 1033-1051.
Cell Cycle Array Products ...