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Anti-phospho-4E Binding Protein-1 (Thr37/46) (4E-BP1, PHAS-1)
Anti-phospho-4E Binding Protein-1 (Thr37/46) (4E-BP1,...

Item number: 0004-19.100

4E-BP1 (also known as PHAS-1) normally binds eIF4E, inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation (1). The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 (2,3). 4E-BP1 is phosphorylated in vivo on multiple residues (4),...
Application: WB
Host: Rabbit
Species reactivity: human, monkey, mouse, rat
711.00€ *
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