Anti-NMDA Receptor NR1 Subunit

Anti-NMDA Receptor NR1 Subunit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10607-1 1 each -

6 - 10 business days*

564.00€
 
The ion channels activated by glutamate are typically divided into two classes. Glutamate... more
Product information "Anti-NMDA Receptor NR1 Subunit"
The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to Nmethyl- D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1-subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.Immunogen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor. Formulation: (Request formulation change), Affinity-purified IgG. Host: Mouse. Applications: IP and WB. Origin: Animal/Mouse.
Keywords: Anti-Grin1, Anti-NMD-R1, Anti-Nmdar1, Anti-Glutamate [NMDA] receptor subunit zeta-1, Anti-N-methyl-D-aspartate receptor subunit NR1
Supplier: Cayman Chemical
Supplier-Nr: 10607

Properties

Application: IP, WB
Antibody Type: Monoclonal
Conjugate: No
Host: Mouse
Species reactivity: rat
Immunogen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor
Format: Solid

Database Information

KEGG ID : K05208 | Matching products
UniProt ID : P35439 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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