Anti-NMDA Receptor NR2B Subunit

Anti-NMDA Receptor NR2B Subunit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10609-1 1 each -

6 - 10 business days*

564.00€
 
The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are... more
Product information "Anti-NMDA Receptor NR2B Subunit"
The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy. and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be clonedand it can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Overexpression of the NR2B-subunit of the NMDA receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. The NMDAR is also potentiated by protein phosphorylation.Synonyms: N-methyl-D-aspartate Receptor. Immunogen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor. Formulation: (Request formulation change), Affinity-purified IgG. Host: Rabbit. Applications: IHC, IP, and WB. Origin: Animal/Rabbit.
Keywords: N-methyl-D-aspartate Receptor
Supplier: Cayman Chemical
Supplier-Nr: 10609

Properties

Application: IHC, IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: rat
Immunogen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor
Format: Solid

Database Information

KEGG ID : K05210 | Matching products
UniProt ID : Q00960 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-NMDA Receptor NR2B Subunit"
Write a review
or to review a product.
Viewed