Anti-BNIP3L

Anti-BNIP3L
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-843A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A302-843A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins.... more
Product information "Anti-BNIP3L"
Protein function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. [The UniProt Consortium]
Keywords: Anti-NIP3L, Anti-BNIP3L, Anti-BNIP3A, Anti-NIP3-like protein X, Anti-Adenovirus E1B19K-binding protein B5, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Supplier: Bethyl Laboratories
Supplier-Nr: A302-843A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, bovine)
Immunogen: synthetic peptide. The epitope recognized by A302-843A maps to a region between residue 169 and 219 of human BCL2/Adenovirus E1B 19kDa Interacting Protein 3-Like using the numbering given in entry NP_004322.1 (GeneID 665).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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