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Acute Phase Response

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Find here a list of antibodies against proteins involved in acute phase reaction.

Background


These are proteins involved in acute phase, a response of the vertebrate body to insults, infections, immunological reactions or inflammatory processes; characterised by redness (rubor), heat (calor), swelling (tumor), pain (dolor) and sometimes loss of function. Acute-phase proteins are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. In response to injury, local inflammatory cells (neutrophil granulocytes and macrophages) secrete a number of cytokines into the bloodstream, most notable of which are the interleukins IL-1, IL-6 and IL-8, and TNF-α. The liver responds by producing a large number of acute-phase reactants. At the same time, the production of a number of other proteins is reduced; these are, therefore, referred to as "negative" acute-phase reactants.

Antibodies to Proteins involved in Acute Phase Response


References


http://www.uniprot.org/keywords/KW-0011
http://de.wikipedia.org/wiki/Akute-Phase-Protein
http://en.wikipedia.org/wiki/Acute-phase_protein

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