Kontakt 0800-2466651 DE | EN Login Warenkorb


HERSTELLER INFO

Interferons


Biomol offers a wide range of interferon α, β and γ preparations.
Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens.

Interferons


Cytokines are linked to order information of the relavant cytokines, receptors are linked to order information of the relevant antibodies:

Cytokine Size Receptors Producer Cells Actions
IFN-α 166, monomer CD118 (IFNAR2) Leukocytes, dendritic cells Antiviral, increased MCC class I expression
IFN-β 166, monomer CD118 (IFNAR2) Fibroblasts Antiviral, increased MCC class I expression
IFN-γ 143, homodimer CD119 (IFNGR2) T cells, natural killer cells Macrophage activation, increased expression of MHC molecules and antigen processing components, IG class switching, suppresses Th2


IFN-α and IFN-β belong to class I of the interferons, IFN-γ is the member of the class II of interferons. IL-28 and IL-29 are classified as class III interferons. These class III IFNs signal through a receptor complex consisting of IL10R2 (also called CRF2-4 or CD210b) and IFNLR1 (also called CRF2-12).

References


Janeways Immunobiology (7th edition), Kenneth Murphy, Paul Travers, Mark Walport, Garland Science (2008), p. 799
http://en.wikipedia.org/wiki/Interferon

Cytokine Search

 



zurück

HOT LINKS


Forschungsprodukte im Fokus

 

Produkte

Service

Company

€ 10

Gutschein sichern