- Search results for 5632-1
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6 products were found matching "5632-1"!
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Item number: Cay15632-5
SN-38 is an inhibitor of topoisomerase I and an active metabolite of the prodrug irinotecan (Cay-14180). It is formed from irinotecan by carboxylesterases. SN-38 (0.1, 1, and 10 µM) induces topoisomerase I-dependent DNA cleavage in a cell-free assay. It induces DNA single-strand breaks in HT-29 colorectal...
Keywords: | 7-ethyl-10-hydroxy-20(S)-Camptothecin, 7-Ethyl-10-Hydroxycamptothecin, NK 012,... |
Application: | Potent DNA topoisomerase I inhibitor |
CAS | 86639-52-3 |
MW: | 392.4 D |
From 66.00€
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Item number: Cay25632-1
Compound 43 TAO kinase inhibitor is an ATP-competitive inhibitor of the thousand-and-one amino acid kinases TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Compound 43 TAO...
Keywords: | N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide |
Application: | ATP-competitive TAOK1 / TAOK2 inhibitor |
CAS | 850467-66-2 |
MW: | 384.5 D |
From 43.00€
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Item number: Cay35632-1
Salvigenin is a polyphenol flavonoid originally found in Alnus japonica with diverse biological activities. It inhibits hydrogen peroxide-induced apoptosis and reduces the generation of reactive oxygen species (ROS) in SH-SY5Y human neuroblastoma cells when used at a concentration of 25 µM. Salvigenin (25 and 50 µM)...
Keywords: | 5-hydroxy-4',6,7-Trimethoxyflavone, 7-O-Methylpectolinarigenin, Psathyrotin,... |
Application: | Bioactive polyphenol flavonoid |
CAS | 19103-54-9 |
MW: | 328.3 D |
From 85.00€
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Item number: VMPS-5632
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Tip49, Ruvbl1, TIP49a, Pontin 52, RuvB-like 1, EC=3.6.4.12, DNA helicase p50, 49 kDa TBP-interacting protein, 49 kDa TATA... |
Application: | RNA quantification |
43.00€
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Item number: ELK-ES5632.100
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several...
Keywords: | Anti-phospho-GRF2, Anti-phospho-RAPGEF1, Anti-phospho-Protein C3G, Anti-phospho-CRK SH3-binding GNRP, Anti-phospho-Guanine... |
Application: | WB, IHC, IF, ELISA |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
From 169.00€
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Item number: 245632.100
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive...
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | human |
699.00€
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