- Search results for 6664-1
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15 products were found matching "6664-1"!
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Item number: Cay16664-10
Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: | OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,... |
Application: | Arginine vasopressin receptor 2 (AVPR2) antagonist |
CAS | 138470-70-9 |
MW: | 464 D |
From 48.00€
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Item number: Cay26664-1
3'-Ethoxy spinosyn L is a minor component of the insecticide spinetoram (Cay-26623). Formulations containing 3'-ethoxy spinosyn L have been used as insecticides.Formal Name:...
Keywords: | Spinetoram L,... |
Application: | Minor spinetoram component |
CAS | 187166-15-0 |
MW: | 760 D |
From 265.00€
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Item number: Cay36664-1
E3 ligase ligand 2 is an active metabolite of thalidomide (Cay-14610) and an intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs) containing thalidomide, a ligand for the E3 ubiquitin ligase cereblon (CRBN), used in targeted protein degradation. E3 ligase ligand 2 is formed from thalidomide via...
Keywords: | 4-hydroxy Thalidomide, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione |
Application: | Thalidomide active metabolite, PROTAC synthetic intermediate |
CAS | 5054-59-1 |
MW: | 274.2 D |
From 40.00€
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Item number: E-AB-66264.120
This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F...
Keywords: | Anti-CAND1, Anti-KIAA0829, Anti-p120 CAND1, Anti-TBP-interacting protein 120A, Anti-TBP-interacting protein of 120 kDa A,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: E-AB-66364.120
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. Protein function: Forms a complex with DNA polymerase epsilon...
Keywords: | Anti-CHRAC1, Anti-CHRAC-1, Anti-CHRAC15, Anti-CHRAC-15, Anti-HuCHRAC15, Anti-DNA polymerase epsilon subunit p15,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 218.00€
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Item number: E-AB-66604.120
Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]). Protein function: Nicotinic acid adenine dinucleotide phosphate (NAADP)...
Keywords: | Anti-TPCN1, Anti-KIAA1169, Anti-Two pore calcium channel protein 1, Anti-Voltage-dependent calcium channel protein TPC1,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
From 198.00€
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Item number: E-AB-66624.120
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Protein function: PPIases accelerate the folding of proteins....
Keywords: | Anti-PPIL4, Anti-PPIase, EC=5.2.1.8, Anti-Rotamase PPIL4, Anti-Cyclophilin-like protein PPIL4, Anti-Peptidyl-prolyl... |
Application: | IF |
Host: | Rabbit |
Species reactivity: | human |
From 198.00€
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Item number: E-AB-66694.120
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for...
Keywords: | Anti-HEY1, Anti-HRT-1, Anti-CHF-2, Anti-hHRT1, Anti-HESR-1, Anti-BHLHB31, Anti-bHLHb31, Anti-HES-related repressor protein... |
Application: | IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: E-AB-66764.120
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important...
Keywords: | Anti-HspB1, Anti-HSP27, Anti-HSPB1, Anti-SRP27, Anti-HSP 27, Anti-28 kDa heat shock protein, Anti-Heat shock 27 kDa... |
Application: | WB, IHC, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 218.00€
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Item number: E-AB-66964.120
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of...
Keywords: | Anti-B1F, Anti-hB1F, Anti-NR5A2, Anti-LRH-1, Anti-B1-binding factor, Anti-Liver receptor homolog 1, Anti-CYP7A... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 198.00€
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Item number: Cay29984-2.5
Streptimidone is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits protein synthesis in a cell-free assay when used at a concentration of 50 µg/ml. It reduces tumor growth in H.S. No. 1 human sarcoma and H.Ep. No. 3 human epidermoid carcinoma rat xenograft...
Keywords: | Ao58A, NSC 66645, 4-[(2R,5S,6E)-2-hydroxy-5,7-dimethyl-4-oxo-6,8-nonadien-1-yl]-2,6-piperidinedione |
Application: | Bioactive bacterial metabolite |
CAS | 738-72-7 |
MW: | 293.4 D |
From 239.00€
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Item number: E-AB-66640.120
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in...
Keywords: | Anti-ANT1, Anti-ANT 1, Anti-SLC25A4, Anti-ADP/ATP translocase 1, Anti-ADP,ATP carrier protein 1, Anti-Adenine nucleotide... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
From 198.00€
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