- Search results for A300-738A
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30 products were found matching "A300-738A"!
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Item number: A300-783A-T
Protein function: Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral...
Keywords: | Anti-VISA, Anti-MAVS, Anti-IPS1, Anti-IPS-1, Anti-Cardif, Anti-Virus-induced-signaling adapter, Anti-CARD adapter inducing... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-873A-T
Protein function: Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. [The UniProt Consortium]
Keywords: | Anti-RCC2, Anti-KIAA1470, Anti-Protein RCC2, Anti-RCC1-like protein TD-60, Anti-Telophase disk protein of 60 kDa |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-778A
Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with...
Keywords: | Anti-PBEF, Anti-NAMPT, Anti-Nampt, Anti-Visfatin, Anti-NAmPRTase, EC=2.4.2.12, Anti-Pre-B cell-enhancing factor,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-788A
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two...
Keywords: | Anti-phospho-BM28, Anti-phospho-MCM2, EC=3.6.4.12, Anti-phospho-Nuclear protein BM28, Anti-phospho-DNA replication... |
Application: | WB, IHC, FC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-748A
Protein function: Acts as component of the WTAP complex that is involved in RNA processing and cell cycle (PubMed:24100041). [The UniProt Consortium]
Keywords: | Anti-ZC3H13, Anti-KIAA0853, Anti-Zinc finger CCCH domain-containing protein 13 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-708A
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress...
Keywords: | Anti-CSBP, Anti-MAPK14, Anti-SAPK2a, Anti-MAPK 14, Anti-MAP kinase 14, Anti-MAP kinase MXI2, Anti-MAP kinase p38 alpha,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-728A
Protein function: Involved in DNA damage response, activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for...
Keywords: | Anti-BAAT1, Anti-BRAT1, Anti-BRCA1-associated ATM activator 1, Anti-BRCA1-associated protein required for ATM activation... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-768A
Protein function: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances...
Keywords: | Anti-TORC-1, Anti-Transducer of CREB protein 1, Anti-CREB-regulated transcription coactivator 1, Anti-Mucoepidermoid... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-798A
Protein function: Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand- dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell...
Keywords: | Anti-NIF-1, Anti-ZNF335, Anti-Zinc finger protein 335, Anti-NRC-interacting factor 1 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-038A
Protein function: RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation, its phosphorylation appears to be a key step in NMD. Recruited...
Keywords: | Anti-UPF1, Anti-hUpf1, Anti-NORF1, Anti-KIAA0221, EC=3.6.4.-, Anti-ATP-dependent helicase RENT1, Anti-Nonsense mRNA... |
Application: | WB, IP |
Host: | Goat |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-138A
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1,...
Keywords: | Anti-ATR, Anti-FRP1, EC=2.7.11.1, Anti-FRAP-related protein 1, Anti-Serine/threonine-protein kinase ATR, Anti-Ataxia... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-739A
Protein function: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase...
Keywords: | Anti-CUL4A, Anti-CUL-4A, Anti-Cullin-4A |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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