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Histone H4 (human, recombinant)
Histone H4 (human, recombinant)

Item number: Cay10264-100

A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H4 undergoes many...
Keywords: H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4-16, HIST4H4, Histone H4, Histone H4
Application: TR-FRET
Expressed in: E.coli
Origin: human
MW: 11,5 kD
130.00€ *
Review
Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)

Item number: Cay10261-1

Histone H2A is a core histone that forms a dimer with histone H2B. Two histone H2A/H2B dimers form an octameric nucleosome with a histone H3/H4 tetramer, around which DNA wraps, allowing it to be condensed. Histone H2A can be post-translationally modified via methylation of the arginine at position 3 by protein...
Keywords: Histone H2A type 1, Histone H2A type 1
Application: WB
Expressed in: E.coli
MW: 13,9 kD
726.00€ *
Review
JGB1741
JGB1741

Item number: Cay10641-1

The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to longevity, cancer, gene regulation, energy homeostasis, and apoptosis. JGB1741 is a small molecule inhibitor of SIRT1 with an IC50 value of 15 µM in a cell-free assay. It shows relatively weak...
Keywords: ILS-JGB-1741,...
Application: SIRT1 inhibitor
CAS 1256375-38-8
MW: 440.6 D
From 86.00€ *
Review