Cayman Chemical: Receptor Antagonists

A receptor antagonist is a receptor ligand that does not provoke a biological response itself upon binding to a receptor, but blocks or subdues agonist-mediated responses.

AG-041R (gastrin/cholecystokinin-2 (CCKB) receptor antagonist)
Agomelatine (antagonist of human and porcine serotonin (5-HT2C) receptors )
AH 23848 (calcium salt, hydrate) (dual antagonist of TP and EP4 receptors)
AM630 (selective CB2 receptor antagonist)
AVE-1625 (highly potent, selective antagonist for the CB1 receptor)
Capsazepine (competitive antagonist of transient receptor potential vanilloid type 1 TRPV1)
CAY10500 (TNF Receptor 1 (TNFR1) antagonist)
CAY10580 (binds the EP4 receptor)
CAY10595 (potent CRTH2/DP2 receptor antagonist)
CAY10597 (CRTH2/DP2 receptor antagonist)
Clobenpropit (hydrobromide) (selective histamine H3 receptor antagonist)
(E)-Guggulsterone (competitive antagonist of FXR)
GW 627368X (competitive antagonist of the EP4 receptor)
GW 848687X (potent and selective EP1 receptor antagonist )
GW 9662
GW 9662-d5
JMV3002 (potent ghrelin receptor antagonist)
JTE-013 (potent, selective sphingosine-1-phosphate 2 (S1P2) receptor antagonist)
Ki16425 (LPA receptor antagonist)
L-655,240 (potent antagonist of the TP receptor)
LY223982 (BLT1 receptor antagonist)
LY293111 (potent antagonist of the LTB4 receptor BLT1)
MK 0524 (DP1 receptor antagonist)
NESS 0327 (potent cannabinoid (CB) receptor antagonist)
Plerixafor (hydrochloride hydrate) (irreversible antagonist of CXCR4)
Raloxifene (hydrochloride) (selective estrogen receptor modulator )
Rimonabant (CB1 receptor inverse agonist)
SKF-96365 (hydrochloride) (inhibits voltage-gated calcium channels)
T0070907 (elective histamine H3 receptor antagonist)
Thioperamide Maleate
URB447 (CB1 antagonist/CB2 agonist)
W140 (S1P1 antagonist)
(Z)-Guggulsterone (competitive antagonist of FXR)