- Search results for Cay10319-25
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8 products were found matching "Cay10319-25"!
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Item number: Cay10009317-25
Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: | Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,... |
Application: | Procaspase-3 activator |
CAS | 315183-21-2 |
MW: | 392.5 D |
From 145.00€
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Item number: Cay10319-100
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and...
Keywords: | PRSET7, PR-Set7, PR-Set7, PR/SET07, PR/SET07, H4-K20-HMTase KMT5A, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A,... |
Application: | Enzyme activity |
Expressed in: | E.coli |
MW: | 21.1 kD |
537.00€
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Item number: Cay10329-100
Transsulfuration and reverse transsulfuration comprise part of the metabolic interconversion of the sulfur-containing amino acids cysteine and methionine. Reverse transsulfuration is catalyzed by the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CGL) in fungi and mammals. Specifically, CGL...
Keywords: | CTH, Gamma-cystathionase, Gamma-cystathionase, Cystathionine gamma-lyase, Cystathionine gamma-lyase, Cysteine-protein... |
Application: | Enzyme activity |
MW: | 44,5 kD |
636.00€
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Item number: Cay10010399-25
SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
Keywords: | 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol |
Application: | MAP kinases Inhibitor |
CAS | 152121-30-7 |
MW: | 331.3 D |
From 39.00€
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Item number: Cay10010339-25
Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: | 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal... |
Application: | NF-kappaB activation inhibitor |
CAS | 75225-50-2 |
MW: | 444.5 D |
From 50.00€
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Item number: Cay10011349-25
Dimebolin is a neuroprotective agent. It binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as alpha1A-, alpha1B-, alpha1D-, and alpha2A-adrenergic receptors (ARs), imidazoline I2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 8-313...
Keywords: | Dimebon, Latrepirdine, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole,... |
Application: | Neuroprotective agent |
CAS | 97657-92-6 |
MW: | 392.4 D |
From 31.00€
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Item number: Cay10325-1
Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages. This receptor is also expressed in brain, liver, lung, and kidney tissues. Chemerin, or TIG2, has been identified as the natural ligand for this receptor. Resolvin E1 has also...
Keywords: | Anti-CMKLR1, Anti-CHEMR23, Anti-Chemokine-like receptor 1, Anti-Chemokine-like receptor 1, Anti-G-protein coupled receptor... |
Application: | FC, IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay10315-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Keywords: | SIRT6, SIR2L6, SIR2-like protein 6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2... |
Application: | Enzyme kinetics, Inhibitor screening |
595.00€
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