2-Methoxyestradiol ELISA Kit

2-Methoxyestradiol ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay582261-96S 96 so-wells (96 solid wells) -

6 - 10 business days*

621.00€
Cay582261-96 96 st-wells (96 strip wells) -

6 - 10 business days*

621.00€
Cay582261-480S 480 so-wells (480 solid wells) -

6 - 10 business days*

2,324.00€
Cay582261-480 480 st-wells (480 strip wells) -

6 - 10 business days*

2,324.00€
 
2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant... more
Product information "2-Methoxyestradiol ELISA Kit"
2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant hydroxylation followed by catechol-O-methyltransferase-catalyzed O-methylation. Deficiency in catechol-O-methyltransferase is associated with pre-eclampsia. Therefore, 2-ME2 may be utilized as a plasma and urinary diagnostic marker for this disease, as well as a therapeutic supplement for its prevention. Several clinical trials have demonstrated the antitumor effects of 2-ME2 in prostate cancer, breast cancer, renal cell carcinoma, ovarian cancer, glioblastoma, and multiple myeloma. Other studies indicate that 2-ME2 exhibits more potent cardioprotective effects than estradiol. Cayman's 2-Methoxyestradiol ELISA Kit is a competitive assay that can be used for quantification of 2-ME2 in plasma, urine, and other sample matrices.Synonyms: 2-Hydroxyestradiol 2-methyl ester, 2-ME2 EIA Kit. Assay Range: 13.1-8,000 pg/ml. Sensitivity: 80% B/B0: 40 pg/ml. Mid-point: 50% B/B0: 330-390 pg/ml. Cross Reactivity: (2-Methoxyestradiol) 100%, (Estradiol) 0.29%, (Estrone) 0.04%, (Progesterone) 0.04%, (Testosterone) 0.02%, (Androstenolone) 0.01%, (Estriol) 0.01%, (Cholesterol) <0.01%, (17alpha-Estradiol) <0.01%, (Pregnenolone) <0.01%. Origin: Animal/Mouse, Animal/Bovine, Animal/Eel, Animal/Rabbit.
Keywords: 2-Hydroxyestradiol 2-methyl ester, 2-ME2 EIA Kit
Supplier: Cayman Chemical
Supplier-Nr: 582261

Properties

Application: ELISA
Format: Solid Phase

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H301, H302, H311, H315, H316, H317, H319, H351, H361
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P272, P280, P301+310, P302+352, P303+361+353, P305+351+338, P308+313, P312, P321, P330, P332+313, P333+313, P337+313, P361+364, P362+364, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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