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SET8 Methyltransferase Inhibitor Screening Assay Kit
SET8 Methyltransferase Inhibitor Screening Assay Kit

Item number: Cay700350-96

SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 Methyltransferase Inhibitor Screening Assay provides a convenient...
Keywords: PR-Set7, SET domain-containing (lysine methyltransferase) 8, SETD8
Application: SET8 inhibitor screening
922.00€ *
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Fluprostenol Lactone Diol
Fluprostenol Lactone Diol

Item number: Cay70037-50

Fluprostenol lactone diol is an intermediate used in the preparation of fluprostenol.Formal Name: (+)-(3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-(3-trifluoromethyl)phenoxy-1-butenyl]-2H-cyclopenta[b]furan-2-one. CAS Number: 53872-60-9. Molecular Formula: C18H19F3O5. Formula Weight: 372.3. Purity:...
Keywords: (+)-(3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-(3-trifluoromethyl)phenoxy-1-butenyl]-2H-cyclopenta[b]furan...
Application: Bioactive lipid assays
CAS 53872-60-9
MW: 372.3 D
From 129.00€ *
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Latanoprost Lactone Diol
Latanoprost Lactone Diol

Item number: Cay70039-50

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost lactone diol is an intermediate in the synthesis of latanoprost. Latanoprost lactone diol can be converted to the free acid of latanoprost by reduction with DIBAL followed by Wittig reaction...
Keywords: (3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-2H-cyclopenta[b]furan-2-one
Application: Bioactive lipid assays
CAS 145667-75-0
MW: 304.4 D
From 152.00€ *
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Corey Lactone Aldehyde Benzoate
Corey Lactone Aldehyde Benzoate

Item number: Cay70030-500

Corey lactone aldehyde benzoate is a versatile, chiral intermediate used in the preparation of prostaglandins and prostaglandin analogs.Formal Name: [3aR-(3aalpha,4alpha,5beta,6aalpha)]5-(benzoyloxy)hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde. CAS Number: 39746-01-5. Molecular Formula: C15H14O5. Formula...
Keywords: [3aR-(3aalpha,4alpha,5beta,6aalpha)]5-(benzoyloxy)hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde
Application: Bioactive lipid assays
CAS 39746-01-5
MW: 274.3 D
From 204.00€ *
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SP 141
SP 141

Item number: Cay17003-50

Mouse double minute 2 protein (MDM2) is an E3 ubiquitin-protein ligase that binds and ubiquitinates the tumor suppressor p53, leading to its degradation by the proteasome. SP-141 is a cell-permeable inhibitor of MDM2 (Ki = 28 nM). Binding of MDM2 by SP-141 promotes its auto-ubiquitination and proteasomal...
Keywords: AGN-PC-0D106I, 6-methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole
Application: Cell-permeable Mdm2 inhibitor
CAS 1253491-42-7
MW: 324.4 D
From 60.00€ *
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