- Search results for Cay10010750
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13 products were found matching "Cay10010750"!
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Item number: Cay10010706-50
(-)-Deguelin is a rotenoid that has been found in T. vogelii and has diverse biological activities. It inhibits mitochondrial complex I, also known as NADH dehydrogenase, activity in bovine heart electron transport particles and phorbol 12-myristate 13-acetate-induced ornithine decarboxylase (ODC) activity in MCF-7...
Keywords: | (-)-cis-Deguelin, 13,13aS-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-[1]benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aS)-one |
Application: | Chemopreventive effector |
CAS | 522-17-8 |
MW: | 394.4 D |
From 70.00€
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Item number: Cay10010785-50
(±)-Lisofylline (LSF) is a potent anti-inflammatory agent in which only the (-) optical isomer is biologically active. LSF inhibits the generation of phosphatidic acid (IC50 = 0.6 µM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock. LSF...
Keywords: | BL 194, CT-1501R, LSF, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione |
Application: | Phosphatidic acid generation inhibitor |
CAS | 6493-06-7 |
MW: | 280.3 D |
From 98.00€
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Item number: Cay10010-50
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 14152-28-4 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10010337-50
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate |
Application: | Hydroxymethylglutaryl-coenzyme A reductase inhibitor |
MW: | 410.5 D |
From 35.00€
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Item number: Cay10010947-50
Hydrogen sulfide (H2S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. H2S is synthesized naturally in a range of mammalian tissues principally by the activity of two enzymes, cystathionine gamma lyase (CSE) and cystathionine beta synthetase (CBS). beta-cyano-L-Alanine...
Keywords: | BCA, 3-cyano-L-alanine |
Application: | CSE inhibitor |
CAS | 6232-19-5 |
MW: | 114.1 D |
From 12.00€
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Item number: Cay10011207-50
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | 3-O-C6-(L)-HSL, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-hexanamide |
Application: | Antibiotic |
CAS | 143537-62-6 |
MW: | 213.2 D |
From 40.00€
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Item number: Cay10010547-50
2-Arachidonoyl glycerol (2-AG) is an endogenous ligand that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and is involved in the regulation of a broad range of neurotransmitter signalling functions with implications in neurodegenerative diseases, pain, cancer, and obesity. Levels...
Keywords: | 5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester |
Application: | Fatty acid amide hydrolase inhibitor |
CAS | 439146-24-4 |
MW: | 360.5 D |
From 110.00€
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Item number: Cay10010637-50
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific...
Keywords: | 17R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 183509-24-2 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10010117-50
CB-52 is a stable analog of Delta9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 210 and 30 nM, respectively. In vitro, CB-52 behaves primarily as a CB1 receptor partial agonist and a CB2...
Keywords: | N-cyclopropyl-11-(2-hexyl-5-hydroxyphenoxy)-undecanamide |
Application: | CB1 receptor partial agonist, CB2 receptor neutral antagonist |
CAS | 869376-90-9 |
MW: | 417.6 D |
From 43.00€
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Item number: Cay10010267-50
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
Keywords: | 4-amino-[2,3'-bithiophene]-5-carboxamide |
Application: | IKK2 inhibitor |
CAS | 354812-17-2 |
MW: | 224.3 D |
From 60.00€
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Item number: Cay10010517-50
2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2,3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of...
Keywords: | 1-(4-chlorobenzoyl)-4-[[4-(4,5-dihydro-2-oxazolyl)phenyl]methylene]-piperidine |
Application: | OSC inhibitor |
CAS | 156635-05-1 |
MW: | 380.9 D |
From 60.00€
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Item number: Cay10010907-50
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-622 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.99 and 0.033 µM when preincubated with human recombinant FAAH for 5 and 60 minutes,...
Keywords: | N-phenyl-4-(2-quinolinylmethyl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 898235-65-9 |
MW: | 346.4 D |
From 34.00€
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