An epitope is an antigenic determinant, a biological structure or sequence to which an antibody binds.
Recombinant DNA technology allows us to construct fusion proteins which each consist of a gene of interest and an epitope tag. These fusion proteins can be identified and purified by using epitope tag specific antibodies, which cut the time-consuming and labor-intensive task of antibody generation from already complicated process:
Click on the red dots in the following table for order information:
ECS (DDDDK) tagged proteins are also known as flag-tagged proteins. FLAG™ and ANTI-FLAG™ are a registered trademarks of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.