Daidzein

Daidzein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10005166-100 100 mg -

6 - 10 business days*

20.00€
Cay10005166-500 500 mg -

6 - 10 business days*

77.00€
 
Daidzein is an isoflavone phytoestrogenic compound that has been found in soybeans and other... more
Product information "Daidzein"
Daidzein is an isoflavone phytoestrogenic compound that has been found in soybeans and other legumes. It binds to estrogen receptor beta (ERbeta, Ki = 2.8 µM) but not ERalpha at concentrations up to 1 mM. It is estrogenic in vitro, increasing gene transcription mediated by the estrogen response element (ERE) in a reporter assay in an ERbeta-dependent manner (EC50 = 2.8 µM for MCF-7 cells expressing ERbeta). Daidzein is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). It reduces tumor growth in a PC3 prostate cancer mouse orthotopic model when administered at a dose of 50 mg/kg per day and potentiates the effects of radiation therapy.Formal Name: 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 486-66-8. Molecular Formula: C15H10O4. Formula Weight: 254.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.15 mg/ml, Ethanol: 0.1 mg/ml. lambdamax: 249, 301 nm. SMILES: Oc1ccc(cc1)c1coc2cc(O)ccc2c1=O. InChi Code: InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H. InChi Key: ZQSIJRDFPHDXIC-UHFFFAOYSA-N. Origin: Synthetic.
Keywords: 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Supplier: Cayman Chemical
Supplier-Nr: 10005166

Properties

Application: Metabolic studies
MW: 254.2 D
Formula: C15H10O4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 486-66-8| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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