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The cluster of differentiation (CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells. The CD system is commonly used as cell markers, allowing cells to be defined based on what molecules are present on their surface.
Expression (+) or lack of expression(-) of certain CD markers define certain cell populations. Examples:
|Type of cell||CD markers|
|stem cells||CD34+, CD31-|
|all leukocyte groups||CD45+|
|T lymphocyte||CD45+, CD3+|
|T helper cell||CD45+,CD3+, CD4+|
|Cytotoxic T cell||CD45+,CD3+, CD8+|
|B lymphocyte||CD45+, CD19+ or CD45+, CD20+|
|Natural killer cell||CD16+, CD56+,CD3-|
For phenotyping of dendritic cells we recommend Imgenex Dendritic Cell Phenotyping Kits
|Download your Ancell CD Antibody Brochure
(pdf, 4 pages, 1.7 MB).