2 products were found matching "Cay10004985"!

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Caylin-1
Caylin-1

Item number: Cay10004985-5

Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 is a nutlin-3 analog which contains chlorine substituents at the 3 and 4 positions on two of the phenyl rings rather than a single 4-chloro as seen in nutlin-3. At high...
Keywords: 4-[4,5-bis(3,4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carboxyl]-piperazin-2-one
Application: Nutlin-3 analog
CAS 1207480-88-3
MW: 650.4 D
From 85.00€ *
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HA-130
HA-130

Item number: Cay10498-5

HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM. It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...
Keywords: B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid
Application: Reversible autotaxin inhibitor
CAS 1229652-21-4
MW: 463.3 D
From 97.00€ *
Review