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Caspase Substrates, Inhibitors, and Assay Kits


Find inhibitors, photometric or fluorimetric substrates and assay kits for caspase research.

Caspase Inhibitors


Caspase-3: Ac-DEVD-CHO
Caspase-8: Ac-IETD-CHO

Caspase Substrates


Photometric Substrates


Caspase 3: Ac-DEVD-pNA und Z-DEVD-pNA
Caspase 8: Z-IETD-pNA

Fluorimetric Substrates


The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. FITC-DEVD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. Z is short for Carboxybenzyl (Cbz).
Caspase-3 and Caspase-7: Ac-DEVD-AFC, Ac-DEVD-AMC, FITC-C6-DEVD-FMK, Z-DEVD-AFC, Z-DEVD-AMC, (Z-DEVD)2-R110
Caspase-8: Ac-IETD-AFC, Ac-IETD-AMC, Z-IETD-AFC, (Z-IETD)2-R110
Caspase-9: Ac-LEHD-AMC, (Ac-LEHD)2-R110

Caspase Assay Kits


Caspase 3: Amplite(TM)Fluorimetric Caspase 3 Assay Kit *Blue Fluorescence*, Amplite(TM)Fluorimetric Caspase 3 Assay Kit *Green Fluorescence*
Amplite™ is an enzyme-based detection platform.
Caspase 3 and Caspase 7: Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit * Blue Fluorescence*, Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit * Green Fluorescence*
Cell Meter™: assay kits for functional analysis of cellular events.

ABD Bioquest Caspase Products ...

 



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