Cytokines are signaling proteins in cellular communication.
While hormones are secreted from specific organs to the blood, and neurotransmitters are related to neural activity, the cytokines are a more diverse class of compounds in terms of origin and purpose. They are produced by a wide variety of hematopoietic and non-hematopoietic cell types and can have autocrine, paracrine and endocrine effects, sometimes strongly dependent on the presence of other chemicals. The cytokine family consists mainly of smaller, water-soluble proteins and glycoproteins with a mass between 8 and 30 kDa.
The term cytokine is used generically for interleukins
, growth factors
and similar extracellular proteinaceous ligands (lymphokines, monokines, interferons
, colony-stimulating factors
, immunomodulators, immunotransmitters, etc.).
Cytokines can be isolated from natural sources or are recombinant and produced in bacteria
or higher eukaryotic cells
. Wheras bacterially expressed ones lack post-translational modifications, the latter are glycoproteins. In many assays non-glycosylated cytokines show a similar activity as glycosylated ones, for some studies glycosylation is important.
Cytokine Product Line
, and Humanzyme
produce more than 1000 cytokines, all available from Biomol .
At Biomol you find this extensive range of cytokines:
Alphabetic Listing of Cytokines
4, A, B, C, E, F, G, H, I, K, L, M, N, O, P, R, S, T, V
Clean and glycosylated cytokines (very low endotoxin) expressed in plants (barley grain): bio-clean cytokines
About 400 of Biomols cytokines are presented in this pdf document
Biomol offers a range of human cytokines, which have been recombinantly produced in human cell lines. They carry authentic glycosyslation making them more stable and active:
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HumaXPress Human Cell Line Expressed Cytokines
Cytokine and Ligand ELISA Kits
Biomol offers a selection of affordable and easy-to-use ELISA kits
for determination of concentration cytokines (and similar ligands).
Biomol offers also thousands of antibodies
for the analysis of cytokines and similar ligands.
Find your cytokine here ...