New MyD88 Monoclonal Antibody Clone 4D6
This monoclonal antibody to MyD88
is ideal for studying TLR, IL-1 and IFNγ signaling.MyD88
is a major adaptor molecule involved in TLR, IL-1 and IFNγ signaling pathways. Cell activation through TLRs leads to MyD88 mediation of NF-κB as well as Erk, Jnk and p38 signaling pathways involved in inflammatory mediator gene transcription. IFNγ activation of MyD88 leads to p38 activation and downstream regulation of TNF and IP-10 transcripts.
The MyD88 specific monoclonal antibody (4D6
), along with our other adaptor molecule reagents specific to TRIF
, enable development of assays, read-out systems and potential target development for cell signaling, control especially for Western Blot, Flow Cytometry or IHC applications.
MyD88 monoclonal antibody clone 4D6
Alexa Fluor 488 conjugated: IMG-6625AF488