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Z-VDVAD-aminoluciferin
Artikelnummer: ABD-13215
Molecular weight: 912.99. Extinction coefficient (cm^-1 M^-1): 18000 Excitation (nm): 362. Emission (nm): 499. Z-VDVAD-aminoluciferin is a luminogenic substrate that measures caspase-2 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
| Anwendung: | Luminogenic caspase-2 substrate |
| MW: | 912.99 D |
1.810,00 €
Z-VEID-aminoluciferin
Artikelnummer: ABD-13216
Molecular weight: 869.96. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-VEID-aminoluciferin is a luminogenic substrate that measures caspase-6 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
| Anwendung: | Luminogenic caspase-6 substrate |
| MW: | 869.96 D |
1.117,00 €
Z-ATAD-aminoluciferin
Artikelnummer: ABD-13217
Molecular weight: 771.82. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-ATAD-aminoluciferin is a luminogenic substrate that measures caspase-12 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
| Anwendung: | Luminogenic caspase-12 substrate |
| MW: | 771.82 D |
1.117,00 €
Tat-Gap 19 (trifluoroacetate salt)
Artikelnummer: Cay36729-1
Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels. It is composed of the HIV-1 Tat protein transduction domain linked to a nine-amino acid peptide corresponding to residues 128-136 of Cx43. Tat-Gap 19 (10 µM) inhibits glutamate-induced ATP release, a marker of Cx43 hemichannel activity, in primary...
| Schlagworte: | L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutami... |
| Anwendung: | Cx43 (GJA1) hemichannel peptide inhibitor |
| MW: | 2703.3 D |
ab 155,00 €
RS Repeat Peptide (trifluoroacetate salt)
Artikelnummer: Cay37498-1
RS repeat peptide is a serine/arginine-rich peptide substrate for CDC-like kinase 1 (Clk1). It has been used to identify inhibitors of Clk1 with anticancer activity.Formal Name:...
| Schlagworte: | glycyl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-argin... |
| Anwendung: | CDC-like kinase 1 (Clk1) peptide substrate |
| MW: | 1934.1 D |
ab 53,00 €
(BOC-VPR)2R110
Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
139,00 €
MeOSuc-AAPV-pNA
Artikelnummer: Cay17601-10
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
| Schlagworte: | N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide |
| Anwendung: | Neutrophil elastase & PR3 substrate |
| CAS | 70967-90-7 |
| MW: | 590.6 D |
ab 88,00 €
(Ac-WLA)2R110
Artikelnummer: ABD-13468
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
139,00 €
PPACK (hydrochloride)
Artikelnummer: Cay37489-5
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
| Schlagworte: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, D-Phe-Pro-Arg-CH2Cl, Pebac,... |
| Anwendung: | Thrombin-mediated platelet activation inhibitor |
| CAS | 82188-90-7 |
| MW: | 523.9 D |
ab 48,00 €
Abl Substrate Peptide (trifluoroacetate salt)
Artikelnummer: Cay36969-1
Abl substrate peptide is a peptide substrate for the tyrosine kinase Abl. It is selectively phosphorylated by Abl over c-Src kinase at 20 µM. Abl substrate peptide has been used to quantify Abl kinase activity in vitro.Formal Name:...
| Schlagworte: | L-alpha-glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-L-lysin... |
| Anwendung: | Tyrosine kinase Abl peptide substrate |
| MW: | 1336.6 D |
ab 104,00 €
DC432 (trifluoroacetate salt)
Artikelnummer: Cay36980-1
DC432 is a cell-permeable peptide inhibitor of N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1, IC50 = 0.054 µM). It binds to NTMT1 and NTMT2 (Kds = 0.3 and 1 µM, respectively) and inhibits N-terminal dimethylation of regulator of chromosome condensation 1 (RCC1) by NTMT1 in a cell-free assay when used at...
| Schlagworte: | (S)-N-1,28-diamino-6S-carbamoyl-9S,12S,15S,18S,21S-pentakis(3-guanidinopropyl)-1-imino-8,11,14,17,20,23-hexaoxo-2,7,10,13,... |
| Anwendung: | NTMT1 peptide inhibitor |
| MW: | 1313.6 D |
ab 54,00 €
FALGPA (trifluoroacetate salt)
Artikelnummer: Cay37374-1
FALGPA is a colorimetric substrate for collagenase. It is selective for collagenase over trypsin, thermolysin, and elastase. Collagenase preferentially binds to and cleaves the Leu-Gly (LG) peptide sequence to release the furanacryloyl group, which can be quantified by colorimetric detection at 324 to 345 nm as a...
| Schlagworte: | 2-Furanacryloyl-Leu-Gly-Pro-Ala-OH, 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,... |
| Anwendung: | Photometric collagenase substrate |
| MW: | 476.5 D |
ab 35,00 €