Substrate und Inhibitoren

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NucView(R) 488 Caspase-3 Substrate, 1mM in DMSO
NucView(R) 488 Caspase-3 Substrate, 1mM in DMSO

Artikelnummer: BOT-10402

NucView(R) 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time. Unlike conventional caspase assays, NucView(R) 488 Caspase-3 Substrate detects caspase-3/7 activity within individual intact cells without...
ab 111,00 €
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NucView(R) 488 Caspase-3 Substrate, 1mM in 1X PBS
NucView(R) 488 Caspase-3 Substrate, 1mM in 1X PBS

Artikelnummer: BOT-10403

NucView(R) 488 Caspase-3 Substrate is a novel fluorogenic caspase substrate for real-time detection of caspase-3/7 activity in live cells. In apoptotic cells, the substrate is cleaved to release a DNA dye that stains the nucleus with bright green fluorescence. 1 mM in PBS, 100 uL.
ab 111,00 €
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Ac-DEVD-CHO, Caspase-3 Inhibitor (5 mg)
Ac-DEVD-CHO, Caspase-3 Inhibitor (5 mg)

Artikelnummer: BOT-10404

Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for Caspase-3/7, and contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibit Caspase-3/7 activity in apoptotic cells, and to study events downstream of Caspase-3/7 activation.Soluble in DMSOStore at 4°CC20H30N4O11MW:...
ab 121,00 €
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NucView(R) 405 Caspase-3 Substrate, 1 mM in DMSO
NucView(R) 405 Caspase-3 Substrate, 1 mM in DMSO

Artikelnummer: BOT-10405

NucView(R) 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
ab 111,00 €
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NucView(R) 530 Caspase-3 Substrate, 1 mM in DMSO
NucView(R) 530 Caspase-3 Substrate, 1 mM in DMSO

Artikelnummer: BOT-10406

NucView 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting caspase activity in intact cells in real time by either fluorescence microscopy or flow cytometry, the substrate stains apoptotic cell nuclei with orange fluorescence (Ex/Em 528/563 nm).
ab 111,00 €
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NucView(R) 405 Caspase-3 Substrate, 1 mM in 1X PBS
NucView(R) 405 Caspase-3 Substrate, 1 mM in 1X PBS

Artikelnummer: BOT-10407

NucView(R) 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
ab 111,00 €
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NucView(R) 530 Caspase-3 Substrate, 1 mM in 1X PBS
NucView(R) 530 Caspase-3 Substrate, 1 mM in 1X PBS

Artikelnummer: BOT-10408

NucView(R) 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
ab 111,00 €
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Tat-Gap 19 (trifluoroacetate salt)
Tat-Gap 19 (trifluoroacetate salt)

Artikelnummer: Cay36729-1

Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels. It is composed of the HIV-1 Tat protein transduction domain linked to a nine-amino acid peptide corresponding to residues 128-136 of Cx43. Tat-Gap 19 (10 µM) inhibits glutamate-induced ATP release, a marker of Cx43 hemichannel activity, in primary...
Schlagworte: L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutami...
Anwendung: Cx43 (GJA1) hemichannel peptide inhibitor
MW: 2703.3 D
ab 155,00 €
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RS Repeat Peptide (trifluoroacetate salt)
RS Repeat Peptide (trifluoroacetate salt)

Artikelnummer: Cay37498-1

RS repeat peptide is a serine/arginine-rich peptide substrate for CDC-like kinase 1 (Clk1). It has been used to identify inhibitors of Clk1 with anticancer activity.Formal Name:...
Schlagworte: glycyl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-arginyl-L-seryl-L-argin...
Anwendung: CDC-like kinase 1 (Clk1) peptide substrate
MW: 1934.1 D
ab 53,00 €
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TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2]
TF2-HQKLVFFAK-TQ2...

Artikelnummer: ABD-13206

Extinction coefficient (cm^-1 M^-1): 80000. Excitation (nm): 500. Emission (nm): 522, TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2] has much stronger fluoresce upon protease cleavage than the commonly used FRET peptide MCA-HQKLVFFA (K-DNP), a secretase FRET peptide substrate. In addition, the...
Anwendung: Fluorogenic alpha-secretase substrate
868,00 €
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Ac-DEVD-aminoluciferin
Ac-DEVD-aminoluciferin

Artikelnummer: ABD-13210

Molecular weight: 779.79. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Ac-DEVD-aminoluciferin is a luminogenic substrate that measures caspase-3 and -7 activities in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Anwendung: Luminogenic caspase-3/-7 substrate
MW: 779.79 D
120,00 €
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Z-LETD-aminoluciferin
Z-LETD-aminoluciferin

Artikelnummer: ABD-13212

Molecular weight: 871.93. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-LETD-aminoluciferin is a luminogenic substrate that measures caspase-8 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
Anwendung: Luminogenic caspase-8 substrate
MW: 871.93 D
868,00 €
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