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Nigericin sodium salt
Artikelnummer: CDX-N0094-M005
Nigericin is an antibiotic, used as a high affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+. It shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity and disrupts membrane potential of mitochondria. It sprimary use is as a NLRP3 activator in inflammasome research.
| Schlagworte: | Antibiotic X464, Azalomycin M, Polyetherin A, Antibiotic K178, Helexin C |
| Anwendung: | Antibiotic |
| CAS | 28643-80-3 |
| MW: | 746,94 D |
ab 87,00 €
Spiramycin
Artikelnummer: LKT-S6232.5
A macrolide antibiotic. It has been shown to decrease the replication index of humanlymphocytes.
| Schlagworte: | SPM, RP-5337 |
| Anwendung: | Antibiotic, macrolide |
| CAS | 8025-81-8 |
| MW: | 842,05 D |
ab 137,00 €
Mitomycin C
Artikelnummer: Cay11435-5
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S. caespitosus. As an alkylating agent, its activity depends on reductive activation either through low pH or DT-diaphorase or NADH cytochrome c reductase. Activated MMC crosslinks double stranded DNA and is widely used as...
| Schlagworte: | Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980,... |
| Anwendung: | Antitumor antibiotic |
| CAS | 50-07-7 |
| MW: | 334.3 D |
ab 84,00 €
Oligomycin Complex
Artikelnummer: Cay11341-5
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins...
| Anwendung: | ATP synthase inhibitor, Apoptosis inducer |
| CAS | 1404-19-9 |
| MW: | 789,3 D |
ab 43,00 €
Gentamycin (Gentamicin) Sulfate Solution 50mg/ml...
Artikelnummer: G2032.20
Broad spectrum, cell culture antibiotic that is non toxic to viruses and mammalian cells at antibacterial levels. Inhibits growth of gram positive and negative bacteria, and mycoplasma. Inhibits normal protein synthesis by binding to L6 protein of 50S ribosomal subunit. Useful antibiotic for Baculovirus expression...
| CAS | 1405-41-0 |
ab 144,00 €
Actinomycin D
Artikelnummer: Cay11421-5
Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low...
| Schlagworte: | Cosmegen, Dactinomycin, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K,... |
| Anwendung: | Cancer studies, antineoplastic |
| CAS | 50-76-0 |
| MW: | 1255.5 D |
ab 90,00 €
Vancomycin (hydrochloride)
Artikelnummer: Cay15327-1
Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Vancomycin resistance in staphylococcal species has...
| Schlagworte: | Lyphocin, Vancomycin hydrochloride |
| Anwendung: | Antibiotic |
| CAS | 1404-93-9 |
| MW: | 1449.3 D |
ab 77,00 €
Hexetidine
Artikelnummer: Cay38755-100
Hexetidine is an antibacterial and antifungal agent. It is active against the bacteria S. mutans, S. sanguis, E. coli, and Oxford staphylococcus (MIC50s = 11.1, 11.1, 111, and 12.5 µg/ml) and the fungus C. albicans (MIC50 = 16.7 µg/ml). Topical administration of hexetidine (0.2% w/v) slows plaque formation in a rat...
| Schlagworte: | NSC 17764, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidinamine |
| Anwendung: | Antibacterial / antifungal agent |
| CAS | 141-94-6 |
| MW: | 339.6 D |
ab 48,00 €
Antibiotic PF 1052
Artikelnummer: BVT-0338-M001
Antibiotic, Antibacterial, antifungal and phytotoxic. Isolated from Phoma sp.
| Schlagworte: | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methyle... |
| Anwendung: | Bioassays |
| CAS | 147317-15-5 |
| MW: | 429,6 D |
ab 120,00 €
Chloramphenicol (Chloromycetin)
Artikelnummer: C4350.1
Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S...
| CAS | 56-75-7 |
| MW: | 323.13 D |
ab 75,00 €
Ampicillin (sodium salt)
Artikelnummer: Cay14417-25
Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC50s = 0.25, 0.5, 2, 0.12, and 0.25 µg/ml, respectively). In vivo, ampicillin (80 mg/kg, i.v.) reduces cough...
| Schlagworte: | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,... |
| Anwendung: | Antibiotic |
| CAS | 69-52-3 |
| MW: | 371.4 D |
ab 58,00 €
Pseurotin A
Artikelnummer: BVT-0003-M001
Antibiotic, Chitin synthase inhibitor, Cytotoxic, Shows nematicidal activity. Isolated from Aspergillus fumigatus.
| Schlagworte: | (5S,8S,9R)-8-Benzoyl-2-((1S,2S,Z)-1,2-dihydroxyhex-3-en-1-yl)-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-... |
| Anwendung: | Chitin synthase inhibitor |
| CAS | 58523-30-1 |
| MW: | 431,4 D |
ab 95,00 €