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C-CBL-Driven AXL Ubiquitination Intrachain TR-FRET Assay Kit
Artikelnummer: BPS-78823
The C-CBL-driven AXL Ubiquitination Intrachain TR-FRET Assay Kit utilizes a Europium cryptate-labeled Ubiquitin Donor and a Cy5-labeled Ubiquitin Acceptor to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains, this assay does not detect...
| Schlagworte: | UFO, AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO, |
| Anwendung: | Inhibitor screening, drug discovery, HTS, IC50 determination, real-time kinetic analyses |
| Spezies-Reaktivität: | human |
3.070,00 €
FGL1:LAG3 Inhibitor Screening Assay Kit
Artikelnummer: BPS-78824
The FGL1:LAG3 Inhibitor Screening Assay is an AlphaLISA(R)-based assay designed to measure the inhibition of LAG3 binding to FGL1 in a homogeneous 384-reaction format. The assay is straightforward: first, FGL1 and LAG3 are incubated with or without a compound of interest. Then, acceptor and donor beads are added to...
| Schlagworte: | HPS, HP-041, HFREP-1, LFIRE-1, Hepassocin, Fibrinogen-like protein 1, Liver fibrinogen-related protein 1,... |
| Anwendung: | Inhibitor screening (LAG3 FGL1 binding) |
| Spezies-Reaktivität: | human |
1.496,00 €
KRAS(G12V) Isoform B Coupled Nucleotide Exchange Assay Kit
Artikelnummer: BPS-78825
The KRAS(G12V) Isoform B Coupled Nucleotide Exchange Assay Kit is designed for screening and profiling of antagonists/inhibitors of KRAS(G12V), Isoform B, by monitoring the binding of an effector protein such as the Ras binding domain of Raf1 (RBD-cRaf) to KRAS. First, a sample containing GDP-loaded KRAS(G12V)...
| Schlagworte: | KRAS, KRAS2, |
| Anwendung: | Small molecule inhibitor/antagonist screening, HTS, compound counter-screening |
| Spezies-Reaktivität: | human |
1.965,00 €
Activated Protein C (PROC) Assay Kit
Artikelnummer: BPS-78827
The Activated Protein C (APC, also known as PROC) Assay Kit is a 96-well format fluorogenic assay designed to measure the protease activity of Activated Protein C (PROC) for screening and profiling applications. Illustration of the assay principle. The substrate is an internally quenched fluorogenic substrate....
| Schlagworte: | PROC, EC=3.4.21.69, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.425,00 €
CSF1R Kinase Assay Kit
Artikelnummer: BPS-78829
The CSF1R Kinase Assay Kit is designed to measure CSF1R kinase activity for screening and profiling applications using ADP-Glo(R) as a detection reagent.
| Schlagworte: | FMS, CD115, CSF1R, CSF-1R, CSF-1-R, M-CSF-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
789,00 €
MMP26 Fluorogenic Assay Kit
Artikelnummer: BPS-78830
The MMP26 (Matrix metalloproteinase 26) Fluorogenic Assay Kit is designed to measure MMP26 protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
| Schlagworte: | MMP26, MMP-26, Endometase, EC=3.4.24.-, Matrilysin-2, Matrix metalloproteinase-26, |
| Anwendung: | Small molecule MMP26 inhibitor screening/profiling |
| Spezies-Reaktivität: | human |
686,00 €
USP1 Inhibitor Screening Assay Kit
Artikelnummer: BPS-78831
The USP1 Inhibitor Screening Assay Kit is a 96-well format fluorogenic assay designed to measure the activity of the deubiquitinating (DUB) enzyme USP1 for screening and profiling applications. To determine the effect of an inhibitor on USP1 activity, the enzyme should be preincubated with or without the test...
| Schlagworte: | USP1, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.195,00 €
USP5 Inhibitor Screening Assay Kit
Artikelnummer: BPS-78832
The USP5 Inhibitor Screening Assay Kit is a 96-well format fluorogenic assay designed to measure the activity of the deubiquitinating (DUB) enzyme USP5 for screening and profiling applications. To determine the effect of an inhibitor on USP5 activity, the enzyme should be preincubated with or without the test...
| Schlagworte: | USP5, ISOT, EC=3.4.19.12, Isopeptidase T, Ubiquitin thioesterase 5, Deubiquitinating enzyme 5, Ubiquitin carboxyl-terminal... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.231,00 €
UCHL1 Inhibitor Screening Assay Kit
Artikelnummer: BPS-78833
The UCHL1 Inhibitor Screening Assay Kit is a 96-well format fluorogenic assay designed to measure the activity of the deubiquitinating (DUB) enzyme UCHL1 for screening and profiling applications. To determine the effect of an inhibitor on UCHL1 activity, the enzyme should be preincubated with or without the test...
| Schlagworte: | UCHL1, UCH-L1, PGP9.5, PGP 9.5, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5, Ubiquitin carboxyl-terminal... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.195,00 €
3CL Protease (T21I, S144A) (SARS-CoV-2) Assay Kit
Artikelnummer: BPS-78834
The 3CL Protease (T21I, S144A) (SARS-CoV-2) Assay Kit is a 96-well homogeneous fluorogenic assay designed to measure the activity of T21I, S144A mutated 3CL Protease for screening and profiling applications, with no time-consuming washing steps. 3CL inhibitor GC376 is also included as a control. The 3CL Protease...
| Schlagworte: | main protease kit, Mpro, SARS-CoV-2 3CL Protease kit, untagged 3CL kit, 3 CL assay, 3CL Pro kit, nsp5, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | SARS-CoV-2 |
1.894,00 €
3CL Protease (P252L) (SARS-CoV-2) Assay Kit
Artikelnummer: BPS-78839
The 3CL Protease (P252L) (SARS-CoV-2) Assay Kit is a 96-well homogeneous fluorogenic based assay designed to measure the activity of P252L mutated 3CL Protease for screening and profiling applications, with no time-consuming washing steps. 3CL inhibitor GC376 is also included as a control. 3CL inhibitor GC376 is...
| Schlagworte: | main protease kit, Mpro, SARS-CoV-2 3CL Protease kit, untagged 3CL kit, 3 CL assay, 3CL Pro kit, nsp5, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | SARS-CoV-2 |
1.894,00 €
USP20 Inhibitor Screening Assay Kit
Artikelnummer: BPS-78840
The USP20 Inhibitor Screening Assay Kit is a 96-well format fluorogenic assay designed to measure the activity of the deubiquitinating (DUB) enzyme USP20 for screening and profiling applications. To determine the effect of an inhibitor on USP20 activity, the enzyme should be preincubated with or without the test...
| Schlagworte: | hVDU2, USP20, KIAA1003, Ubiquitin thioesterase 20, Deubiquitinating enzyme 20, Ubiquitin carboxyl-terminal hydrolase 20,... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.202,00 €