Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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IL-21 (human) (rec.) (His)
Artikelnummer: CHI-HF-20121-C010
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Schlagworte: | IL21, Za11, IL-21, Interleukin-21, Interleukin-21 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~18 kD |
248,00 €
FLT3 Ligand (human) (rec.) (His)
Artikelnummer: CHI-HF-201FLT3L-C010
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice....
| Schlagworte: | Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, FLT3L, FMS-like Tyrosine Kinase 3 Ligand |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~25 kD |
248,00 €
IL-10 (human): Fc (human) (rec.)
Artikelnummer: CHI-HF-21010-C010
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Schlagworte: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
264,00 €
IL-2 (mouse): Fc (mouse) (rec.)
Artikelnummer: CHI-MF-11002-C010
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Schlagworte: | Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
ab 226,00 €
IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-12010-C010
The extracellular domain of mouse IL-10 (aa 22-178) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-10...
| Schlagworte: | Il10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | mouse |
ab 303,00 €
IL-22 (mouse) (rec.) (His)
Artikelnummer: CHI-MR-10022-C010
Protein function: [The Uniprot Consortium]
| Schlagworte: | Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible... |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
ab 209,00 €
CTRP3 [C1qTNF3] (rat) (rec.) (His)
Artikelnummer: CHI-RR-300CTRP3-C010
CTRP3 (C1qTNF-related protein 3) plays an important role in regulating both embryonic cartilage development and postnatal longitudinal bone growth. CTRP3 stimulation leads to ERK1/2-dependent cell proliferation in human osteosarcoma cell lines.
| Schlagworte: | C1qtnf3 protein, Protein C1qtnf3, Complement C1q Tumor Necrosis Factor-related Protein 3, Secretory Protein CORS26, C1QTNF3 |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | ~33 kD |
187,00 €
IL-2 (human) (rec.) (untagged)
Artikelnummer: CHI-HR-20602-C010
Protein. The extracellular domain of human IL-2 (aa 21-153) with a N-terminal Met. Source: E. coli. Endotoxin content: 95% (SDS-PAGE). Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation...
| Schlagworte: | Interleukin-2, Aldesleukin |
| Exprimiert in: | E.coli |
| MW: | 14 kD |
171,00 €
IL-21 (human) (rec.) (untagged)
Artikelnummer: CHI-HR-20621-C010
Protein. Human IL-21 (aa 23-155) with a N-terminal Met. Source: E. coli. Endotoxin content: 95% (SDS-PAGE). Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular...
| Schlagworte: | Interleukin-21 |
| Exprimiert in: | E.coli |
| MW: | 17 kD |
ab 275,00 €
CD28 (human) (rec.) (His)
Artikelnummer: CHI-HF-201CD28-C100
Recombinant protein. The extracellular domain of human CD28 (aa 19-152) is fused at the C-terminus to a His-tag. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. CD28 and CTLA-4 together with their ligands, CD80 (B7-1) and CD86 (B7-2), constitute one of the...
| Schlagworte: | T-cell-specific surface glycoprotein CD28, TP44 |
| Exprimiert in: | Human cells |
418,00 €
GDF15 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210GDF15-C100
Recombinant protein. The extracellular domain of human GDF15 (aa 197-308) is fused to the N-terminus of the Fc region of human IgG1. Measured by its binding ability in a functional ELISA. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. Growth Differentiation...
| Schlagworte: | Growth/Differentiation Factor 15, GDF-15, Macrophage Inhibitory Cytokine 1, MIC-1, NSAID-activated Gene 1 Protein, NAG-1,... |
| Exprimiert in: | Human cells |
523,00 €
GFRAL (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210GFRAL-C100
Recombinant protein. The extracellular domain of human GFRAL (aa 19-351) is fused to the N-terminus of the Fc region of human IgG1. Measured by its binding ability in a functional ELISA. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. GFRAL (GDNF receptor...
| Schlagworte: | GDNF Family Receptor alpha-like, Gral, Glial Cellline-derived Neurotrophic Factor Receptor alpha-like, GFR alpha-like,... |
| Exprimiert in: | Human cells |
523,00 €