Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Rapamycin
Artikelnummer: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Schlagworte: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Anwendung: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
ab 28,00 €
YM-254890
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Schlagworte: | QS 3666A |
| Anwendung: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
ab 220,00 €
Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
Artikelnummer: AG-35B-0018-C050
Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using...
| Schlagworte: | Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region NIE, Ig gamma-1 chain C region KOL,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 28 kD |
341,00 €
IL-38 (human) (rec.) (His)
Artikelnummer: AG-40A-0191Y-3010
IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F...
| Schlagworte: | FIL1T, IL-38, FKSG75, IL-1HY2, IL-1F10, IL-1 theta, FIL1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1 theta,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18 kD |
ab 264,00 €
Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)
Artikelnummer: AG-40B-0245-C050
Growth and differentiation factor 15 (GDF15, also known as macrophage inhibitory cytokine-1 (MIC-1)), is a member of the transforming growth factor (TGF)-beta superfamily and was initially identified in activated macrophages. GDF15 acts through a recently identified receptor called Glial-derived Neurotrophic Factor...
| Schlagworte: | MIC-1, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 4530 kD |
440,00 €
Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.)
Artikelnummer: AG-40B-0246-C050
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the...
| Schlagworte: | FNDC5, FRCP2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 5530 kD |
440,00 €
IL-23 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Artikelnummer: AG-40B-0248-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Schlagworte: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
| MW: | 7555 kD |
440,00 €
IL-27 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Artikelnummer: AG-40B-0249-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Schlagworte: | p28, Il27, Il27a, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
| MW: | 6260 kD |
440,00 €
Isthmin-1 (human) ELISA Kit
Artikelnummer: AG-45B-0032-KI01
Isthmin-1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain-hindbrain organizer called the isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein containing a signal peptide, a thrombospondin domain and an adhesion-associated domain....
| Schlagworte: | ISM1, C20orf82, Isthmin-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
550,00 €
Spilanthol
Artikelnummer: AG-CN2-0543-M005
Spilanthol is a natural non-toxic compound. It is a sesquiterpene lactone and has been traditionally used in folk medicine. It has sensory properties (pungency, tingling, numbing, mouth-watering) and is an excellent stable model compound for sensory/chemoreception studies like pellitorine and a biological analog of...
| Schlagworte: | Affinin, (2E,6Z,8E)-N-Isobutyldeca-2,6,8-trienamide |
| CAS | 25394-57-4 |
| MW: | 221,3 D |
297,00 €
Inosine
Artikelnummer: AG-CR1-3554-G001
Inosine, an intermediate in purine metabolism, consists of hypoxanthine and ribose. It is an inert purine nucleoside formed by breakdown of adenosine (deamination, known as A-to-I editing that occurs in tRNA and mRNA) or also is generated by the action of 5'-nucleotidase on inosine monophosphate (IMP). Inosine has...
| Schlagworte: | 9-beta-D-Ribofuranosylhypoxanthine, NSC 20262, Hypoxanthine 9-beta-D-ribofuranoside |
| CAS | 58-63-9 |
| MW: | 268,2 D |
ab 22,00 €
Ganglioside GM1 . sodium salt (bovine brain)
Artikelnummer: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
ab 99,00 €